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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [4]
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- Validations
- Immunocytochemistry [1]
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- Product number
- BML-FG6090-0100 - Provider product page
- Provider
- Enzo Life Sciences
- Proper citation
- Enzo Life Sciences Cat#BML-FG6090-0100, RRID:AB_2050678
- Product name
- alpha Fodrin, mAb (AA6)
- Antibody type
- Monoclonal
- Antigen
- Other
- Description
- Partially purified. Liquid. In PBS containing 1.0% BSA and 0.09% sodium azide.
- Isotype
- IgG
- Antibody clone number
- AA6
- Vial size
- 100 µl
Submitted references miR-711 upregulation induces neuronal cell death after traumatic brain injury.
The Blockade of Transmembrane Cl⁻ Flux Mitigates I/R-Induced Heart Injury via the Inhibition of Calpain Activity.
Calpain-mediated cleavage of DARPP-32 in Alzheimer's disease.
The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice.
Sabirzhanov B, Stoica BA, Zhao Z, Loane DJ, Wu J, Dorsey SG, Faden AI
Cell death and differentiation 2016 Apr;23(4):654-68
Cell death and differentiation 2016 Apr;23(4):654-68
The Blockade of Transmembrane Cl⁻ Flux Mitigates I/R-Induced Heart Injury via the Inhibition of Calpain Activity.
Zhang JY, Wu F, Gu XM, Jin ZX, Kong LH, Zhang Y, Zhou JJ, Gao F
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(6):2121-34
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2015;35(6):2121-34
Calpain-mediated cleavage of DARPP-32 in Alzheimer's disease.
Cho K, Cho MH, Seo JH, Peak J, Kong KH, Yoon SY, Kim DH
Aging cell 2015 Oct;14(5):878-86
Aging cell 2015 Oct;14(5):878-86
The nuclear splicing factor RNA binding motif 5 promotes caspase activation in human neuronal cells, and increases after traumatic brain injury in mice.
Jackson TC, Du L, Janesko-Feldman K, Vagni VA, Dezfulian C, Poloyac SM, Jackson EK, Clark RS, Kochanek PM
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2015 Mar 31;35(4):655-66
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2015 Mar 31;35(4):655-66
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Supportive validation
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- Enzo Life Sciences (provider)
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- Experimental details
- Rat primary septo-hippocampal co-cultures (astrocytes and neurons cultured from day E18 rat embyros) were challenged with the pro-apoptotic compound staurosporine or with vehicle (DMSO) for times indicated above. Protein (40 _g) was separated by SDS-PAGE, transferred to PVDF membrane and probed with FG6090. The caspase-3 cleaved 120-kDa fragment of alpha-II-spectrin was detected at a dilution of 1:4000. Western blot provided by courtesy of Dr Brian Pike, University of Florida.
