Antibody data
- Antibody Data
- Antigen structure
- References [4]
- Comments [0]
- Validations
- Western blot [1]
- Immunocytochemistry [1]
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Validation data
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- Product number
- H00002181-B01P - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#H00002181-B01P, RRID:AB_2222429
- Product name
- Mouse Polyclonal ACSL3 Antibody
- Antibody type
- Polyclonal
- Description
- Protein G purified.
- Reactivity
- Human, Simian
- Host
- Mouse
- Isotype
- IgG
- Vial size
- 50 ug
- Storage
- Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Submitted references Cerebellar ataxia disease-associated Snx14 promotes lipid droplet growth at ER-droplet contacts.
The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells.
Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains.
Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells.
Datta S, Liu Y, Hariri H, Bowerman J, Henne WM
The Journal of cell biology 2019 Apr 1;218(4):1335-1351
The Journal of cell biology 2019 Apr 1;218(4):1335-1351
The metabolic capacity of lipid droplet localized acyl-CoA synthetase 3 is not sufficient to support local triglyceride synthesis independent of the endoplasmic reticulum in A431 cells.
Poppelreuther M, Sander S, Minden F, Dietz MS, Exner T, Du C, Zhang I, Ehehalt F, Knüppel L, Domschke S, Badenhop A, Staudacher S, Ehehalt R, Stremmel W, Thiele C, Heilemann M, Füllekrug J
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 Jun;1863(6):614-624
Biochimica et biophysica acta. Molecular and cell biology of lipids 2018 Jun;1863(6):614-624
Acyl-CoA synthetase 3 promotes lipid droplet biogenesis in ER microdomains.
Kassan A, Herms A, Fernández-Vidal A, Bosch M, Schieber NL, Reddy BJ, Fajardo A, Gelabert-Baldrich M, Tebar F, Enrich C, Gross SP, Parton RG, Pol A
The Journal of cell biology 2013 Dec 23;203(6):985-1001
The Journal of cell biology 2013 Dec 23;203(6):985-1001
Activation of LXR increases acyl-CoA synthetase activity through direct regulation of ACSL3 in human placental trophoblast cells.
Weedon-Fekjaer MS, Dalen KT, Solaas K, Staff AC, Duttaroy AK, Nebb HI
Journal of lipid research 2010 Jul;51(7):1886-96
Journal of lipid research 2010 Jul;51(7):1886-96
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: ACSL3 Antibody [H00002181-B01P] - Analysis of ACSL3 expression in transfected 293T cell line by ACSL3 polyclonal antibody. Lane 1: ACSL3 transfected lysate(79.2 KDa). Lane 2: Non-transfected lysate.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunocytochemistry/Immunofluorescence: ACSL3 Antibody [H00002181-B01P] - Analysis of purified antibody to ACSL3 on HeLa cell. (antibody concentration 10 ug/ml)