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Cell line expression
Protein structure
LAMA3
Laminin subunit alpha 3BM600-150kDa, epiligrin, kalinin-165kDa, LAMNA, nicein-150kDa
The protein encoded by this gene belongs to the laminin family of secreted molecules. Laminins are heterotrimeric molecules that consist of alpha, beta, and gamma subunits that assemble through a coiled-coil domain. Laminins are essential for formation and function of the basement membrane and have additional functions in regulating cell migration and mechanical signal transduction. This gene encodes an alpha subunit and is responsive to several epithelial-mesenchymal regulators including keratinocyte growth factor, epidermal growth factor and insulin-like growth factor. Mutations in this gene have been identified as the cause of Herlitz type junctional epidermolysis bullosa and laryngoonychocutaneous syndrome. Alternative splicing and alternative promoter usage result in multiple transcript variants. [provided by RefSeq, Dec 2014]
Top validated antibodies |
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| R&D Systems |  MAB21441 |
1 references | Monoclonal |
WB
ICC
IP
FC
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| Invitrogen Antibodies | MA5-24246 |
Monoclonal |
WB
ICC
IHC
FC
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| Atlas Antibodies | HPA009309 |
1 references | Polyclonal |
ICC
IHC
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| Novus Biologicals | NBP1-89955 |
1 references | Polyclonal |
ICC
IHC
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| St John's Laboratory | STJ93890 |
Polyclonal |
WB
EL
ICC
IHC
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