631702

antibody from BioLegend

Targeting: FOXD3 Genesis, HFH2

Western blot (Data presented on provider website)

Immunocytochemistry (Recommended by provider)

Antibody Data

Product number

631702

Provider

BioLegend

Proper citation

BioLegend Cat#631702, RRID:AB_2105424

Product name

Purified anti-FOXD3

Antibody type

Polyclonal

Antigen

Peptide-KLH

Description

The FOXD3 polyclonal antibody recognizes human FOXD3 also known as Forkhead box protein D3 and HNF3/FH transcription factor genesis. FOXD3 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain, predicted molecular weight 48 kD. FOXD3 binds to the consensus sequence 5'-A[AT]T[AG]TTTGTTT-3' and acts as a transcriptional repressor. Also acts as a transcriptional activator. FOXD3 is essential for multiple developmental processes in the vertebrate embryo, including neural crest development and maintenance of mammalian stem cell lineages. The poly6317 antibody has been shown to be useful for Western blotting.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Vial size

200 µl

Storage

Upon receipt, store frozen at -20°C.

References

Submitted references

FOXD3 regulates migration properties and Rnd3 expression in melanoma cells.

Katiyar P, Aplin AE
Molecular cancer research : MCR 2011 May;9(5):545-52

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FOXD3 is a mutant B-RAF-regulated inhibitor of G(1)-S progression in melanoma cells.

Abel EV, Aplin AE
Cancer research 2010 Apr 1;70(7):2891-900