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Protein structure
CALD1
Caldesmon 1CDM, H-CAD, L-CAD
This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Atlas Antibodies |  HPA008066 |
5 references | Polyclonal |
WB
ICC
IHC
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| Proteintech Group | 20887-1-AP |
3 references | Polyclonal |
WB
EL
ICC
IHC
FC
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| Novus Biologicals | NBP2-67458 |
Monoclonal |
WB
ICC
IP
IHC
FC
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| antibodies-online | ABIN2840882 |
2 references | Polyclonal |
WB
IHC
FC
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| Invitrogen Antibodies | MA5-11626 |
2 references | Monoclonal |
WB
ICC
IHC
|
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