Antibody data

Product number
orb137875 - Provider product page
Provider
Biorbyt
Product name
SPHK1 antibody
Antibody type
Polyclonal
Description
Rabbit polyclonal to SPHK1. SPHK1 (Sphingosine Kinase 1), is an enzyme that in humans is encoded by the SPHK1 gene. Melendez et al. (2000) mapped the SPHK1 gene to chromosome 17q25.2 based on sequence identity with ESTs mapped to this region. Kohama et al. (1998) demonstrated that recombinant mouse Sphk1 can specifically phosphorylate D-erythro-sphingosine and that D, L-threo-dihydrosphingosine and N, N-dimethylsphingosine can act as competitive inhibitors of recombinant Sphk1. Pitson et al. (2000) found that recombinant SPHK1 and endogenous SPHK1 purified from placenta had identical enzymatic characteristics, suggesting posttranslational modification does not effect functional properties.
Reactivity
Human, Mouse
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 μg
Storage
Store at -20°C for one year. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for a longer time.Avoid repeated freezing and thawing.
SPHK1 protein structure - orb137875 shown in red.