Explore
Validate
Learn10394-1-AP
antibody from Proteintech Group
Targeting: CFLAR
c-FLIP, CASH, CASP8AP1, Casper, cFLIP, CLARP, FLAME, FLIP, I-FLICE, MRIT
Western blot
ELISAAntibody data
- Antibody Data
- Antigen structure
- References [8]
- Comments [0]
- Validations
- Western blot [1]
- Immunohistochemistry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- 10394-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10394-1-AP, RRID:AB_2081087
- Product name
- CFLAR/FLIP antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated CFLAR/FLIP antibody (Cat. #10394-1-AP) is a rabbit polyclonal antibody that shows reactivity with human and has been validated for the following applications: IF, IHC, IP, WB,ELISA.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references Exercise ameliorates insulin resistance and improves ASK1-mediated insulin signalling in obese rats.
Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.
YM155 sensitizes HeLa cells to TRAIL-mediated apoptosis via cFLIP and survivin downregulation.
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
CRISPR-mediated upregulation of DR5 and downregulation of cFLIP synergistically sensitize HeLa cells to TRAIL-mediated apoptosis.
Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.
Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line.
Zhang Y, Ye T, Zhou P, Li R, Liu Z, Xie J, Hua T, Sun Q
Journal of cellular and molecular medicine 2021 Dec;25(23):10930-10938
Journal of cellular and molecular medicine 2021 Dec;25(23):10930-10938
Cellular FLICE-like inhibitory protein (cFLIP) critically maintains apoptotic resistance in human lens epithelial cells.
Huangfu J, Hao C, Wei Z, Wormstone IM, Yan H, Fan X
Cell death & disease 2021 Apr 9;12(4):386
Cell death & disease 2021 Apr 9;12(4):386
YM155 sensitizes HeLa cells to TRAIL-mediated apoptosis via cFLIP and survivin downregulation.
Chandrasekaran AP, Poondla N, Ko NR, Oh SJ, Ramakrishna S
Oncology letters 2020 Oct;20(4):72
Oncology letters 2020 Oct;20(4):72
Chidamide induces necroptosis via regulation of c‑FLIPL expression in Jurkat and HUT‑78 cells.
Chi Z, Gao H, Liu H, Wu B, Zhang B, Gu M, Yang W
Molecular medicine reports 2020 Feb;21(2):936-944
Molecular medicine reports 2020 Feb;21(2):936-944
Regorafenib suppresses epidermal growth factor receptor signaling-modulated progression of colorectal cancer.
Liu YC, Tsai JJ, Weng YS, Hsu FT
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2020 Aug;128:110319
CRISPR-mediated upregulation of DR5 and downregulation of cFLIP synergistically sensitize HeLa cells to TRAIL-mediated apoptosis.
Poondla N, Chandrasekaran AP, Heese K, Kim KS, Ramakrishna S
Biochemical and biophysical research communications 2019 Apr 23;512(1):60-65
Biochemical and biophysical research communications 2019 Apr 23;512(1):60-65
Coordinated repression of BIM and PUMA by Epstein-Barr virus latent genes maintains the survival of Burkitt lymphoma cells.
Fitzsimmons L, Boyce AJ, Wei W, Chang C, Croom-Carter D, Tierney RJ, Herold MJ, Bell AI, Strasser A, Kelly GL, Rowe M
Cell death and differentiation 2018 Feb;25(2):241-254
Cell death and differentiation 2018 Feb;25(2):241-254
Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line.
Zhang X, Jiang SJ, Shang B, Jiang HJ
Thoracic cancer 2015 Mar;6(2):202-8
Thoracic cancer 2015 Mar;6(2):202-8
No comments: Submit comment
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Jurkat cells were subjected to SDS PAGE followed by western blot with 10394-1-AP(CFLAR antibody) at dilution of 1:1000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The CFLAR/FLIP antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human CFLAR/FLIP. This antibody recognizes human antigen. The CFLAR/FLIP antibody has been validated for the following applications: ELISA, WB, IHC analysis.
