LPCAT2

This gene encodes a member of the lysophospholipid acyltransferase family. The encoded enzyme may function in two ways: to catalyze the biosynthesis of platelet-activating factor (1-O-alkyl-2-acetyl-sn-glycero-3-phosphocholine) from 1-O-alkyl-sn-glycero-3-phosphocholine, and to catalyze the synthesis of glycerophospholipid precursors from arachidonyl-CoA and lysophosphatidylcholine. The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells. The enzyme may localize to the endoplasmic reticulum and the Golgi. [provided by RefSeq, Feb 2009]

Description

Lysophosphatidylcholine acyltransferase 2

Tissue specificity

Tissue enhanced (bone marrow, thyroid gland)

Subcell location

Endoplasmic reticulum, Lipid droplets

Predicted location

Intracellular, Membrane

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

16 (55509072 - 55586666)

Ensembl ID

ENSG00000087253  (ver. 103.38)

Orthologs

Mouse Lpcat2: ENSMUSG00000033192

UniProt

Q7L5N7

neXtProt

NX_Q7L5N7

Human splice variants
Mouse splice variants

Protein structure