AMM02063G

antibody from Leading Biology

Targeting: CASQ2 PDIB2

Western blot (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Antibody Data

Product number

AMM02063G

Provider

Leading Biology

Product name

CASQ2 / Calsequestrin 2 Antibody (clone 1C6)

Antibody type

Monoclonal

Description

Calsequestrin is a high-capacity, moderate affinity, calcium-binding protein and thus acts as an internal calcium store in muscle. Calcium ions are bound by clusters of acidic residues at the protein surface, especially at the interface between subunits. Can bind around 60 Ca(2+) ions. Regulates the release of lumenal Ca(2+) via the calcium release channel RYR2; this plays an important role in triggering muscle contraction. Plays a role in excitation-contraction coupling in the heart and in regulating the rate of heart beats.

Reactivity

Human

Host

Mouse

Antibody clone number

1C6

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.