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- Antibody Data
- Antigen structure
- References [36]
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- Validations
- Western blot [1]
- Immunoprecipitation [1]
- Immunohistochemistry [2]
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- Product number
- 10237-1-AP - Provider product page
- Provider
- Proteintech Group
- Proper citation
- Proteintech Cat#10237-1-AP, RRID:AB_2183478
- Product name
- S100A11 antibody
- Antibody type
- Polyclonal
- Description
- KD/KO validated S100A11 antibody (Cat. #10237-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, rat, mouse and has been validated for the following applications: FC, IF, IHC, IP, WB, ELISA.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 20ul, 150ul
Submitted references S100A11 Promotes Liver Steatosis via FOXO1-Mediated Autophagy and Lipogenesis.
Plasma membrane wound repair is characterized by extensive membrane lipid and protein rearrangements in vascular endothelial cells.
S100A11 Promotes Glioma Cell Proliferation and Predicts Grade-Correlated Unfavorable Prognosis.
ATPIF1 maintains normal mitochondrial structure which is impaired by CCM3 deficiency in endothelial cells.
The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.
Electroacupuncture Promoted Nerve Repair After Peripheral Nerve Injury by Regulating miR-1b and Its Target Brain-Derived Neurotrophic Factor.
S100 Calcium Binding Protein A11 (S100A11) Promotes The Proliferation, Migration And Invasion Of Cervical Cancer Cells, And Activates Wnt/β-Catenin Signaling.
Activated cholangiocytes release macrophage-polarizing extracellular vesicles bearing the DAMP S100A11.
Proteomics analysis of the matrisome from MC38 experimental mouse liver metastases.
Annexin A7 is required for ESCRT III-mediated plasma membrane repair.
Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma.
Apigenin inhibits growth and induces apoptosis in human cholangiocarcinoma cells.
Knockdown of BC200 RNA expression reduces cell migration and invasion by destabilizing mRNA for calcium-binding protein S100A11.
Calgizzarin (S100A11): a novel inflammatory mediator associated with disease activity of rheumatoid arthritis.
Imaging mass spectrometry for accessing molecular changes during burn wound healing.
S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.
Annexin A1 Tethers Membrane Contact Sites that Mediate ER to Endosome Cholesterol Transport.
S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells.
S100A11 is a migration-related protein in laryngeal squamous cell carcinoma.
Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling.
S100A11 is involved in the regulation of the stability of cell cycle regulator p21(CIP1/WAF1) in human keratinocyte HaCaT cells.
Down-regulation of S100A11, a calcium-binding protein, in human endometrium may cause reproductive failure.
Selective expression of S100A11 in lung cancer and its role in regulating proliferation of adenocarcinomas cells.
Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer.
S100A11 mediates hypoxia-induced mitogenic factor (HIMF)-induced smooth muscle cell migration, vesicular exocytosis, and nuclear activation.
LRRC4 inhibits the proliferation of human glioma cells by modulating the expression of STMN1 and microtubule polymerization.
Ca2+-binding protein S100A11: a novel diagnostic marker for breast carcinoma.
DNA damage-induced translocation of S100A11 into the nucleus regulates cell proliferation.
Novel proteins regulated by mTOR in subependymal giant cell astrocytomas of patients with tuberous sclerosis complex and new therapeutic implications.
Regulation of cellular actin architecture by S100A10.
Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells.
Comparative proteomic analysis of differentially expressed proteins in human pancreatic cancer tissue.
Colon-derived liver metastasis, colorectal carcinoma, and hepatocellular carcinoma can be discriminated by the Ca(2+)-binding proteins S100A6 and S100A11.
Th2 cytokines act on S100/A11 to downregulate keratinocyte differentiation.
Colorectal cancer progression correlates with upregulation of S100A11 expression in tumor tissues.
Rad54B targeting to DNA double-strand break repair sites requires complex formation with S100A11.
Zhang L, Zhang Z, Li C, Zhu T, Gao J, Zhou H, Zheng Y, Chang Q, Wang M, Wu J, Ran L, Wu Y, Miao H, Zou X, Liang B
Cellular and molecular gastroenterology and hepatology 2021;11(3):697-724
Cellular and molecular gastroenterology and hepatology 2021;11(3):697-724
Plasma membrane wound repair is characterized by extensive membrane lipid and protein rearrangements in vascular endothelial cells.
Ashraf APK, Gerke V
Biochimica et biophysica acta. Molecular cell research 2021 Jun;1868(7):118991
Biochimica et biophysica acta. Molecular cell research 2021 Jun;1868(7):118991
S100A11 Promotes Glioma Cell Proliferation and Predicts Grade-Correlated Unfavorable Prognosis.
Wang H, Yin M, Ye L, Gao P, Mao X, Tian X, Xu Z, Dai X, Cheng H
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211011961
Technology in cancer research & treatment 2021 Jan-Dec;20:15330338211011961
ATPIF1 maintains normal mitochondrial structure which is impaired by CCM3 deficiency in endothelial cells.
Wang K, Chen H, Zhou Z, Zhang H, Zhou HJ, Min W
Cell & bioscience 2021 Jan 9;11(1):11
Cell & bioscience 2021 Jan 9;11(1):11
The S100 calcium-binding protein A11 promotes hepatic steatosis through RAGE-mediated AKT-mTOR signaling.
Teng F, Jiang J, Zhang J, Yuan Y, Li K, Zhou B, Zhou X, Liu W, Zhang P, Liu D, Zheng M, Lu Y, Zhang H
Metabolism: clinical and experimental 2021 Apr;117:154725
Metabolism: clinical and experimental 2021 Apr;117:154725
Electroacupuncture Promoted Nerve Repair After Peripheral Nerve Injury by Regulating miR-1b and Its Target Brain-Derived Neurotrophic Factor.
Liu YP, Luo ZR, Wang C, Cai H, Zhao TT, Li H, Shao SJ, Guo HD
Frontiers in neuroscience 2020;14:525144
Frontiers in neuroscience 2020;14:525144
S100 Calcium Binding Protein A11 (S100A11) Promotes The Proliferation, Migration And Invasion Of Cervical Cancer Cells, And Activates Wnt/β-Catenin Signaling.
Meng M, Sang L, Wang X
OncoTargets and therapy 2019;12:8675-8685
OncoTargets and therapy 2019;12:8675-8685
Activated cholangiocytes release macrophage-polarizing extracellular vesicles bearing the DAMP S100A11.
Katsumi T, Guicciardi ME, Azad A, Bronk SF, Krishnan A, Gores GJ
American journal of physiology. Cell physiology 2019 Oct 1;317(4):C788-C799
American journal of physiology. Cell physiology 2019 Oct 1;317(4):C788-C799
Proteomics analysis of the matrisome from MC38 experimental mouse liver metastases.
Yuzhalin AE, Lim SY, Gordon-Weeks AN, Fischer R, Kessler BM, Yu D, Muschel RJ
American journal of physiology. Gastrointestinal and liver physiology 2019 Nov 1;317(5):G625-G639
American journal of physiology. Gastrointestinal and liver physiology 2019 Nov 1;317(5):G625-G639
Annexin A7 is required for ESCRT III-mediated plasma membrane repair.
Sønder SL, Boye TL, Tölle R, Dengjel J, Maeda K, Jäättelä M, Simonsen AC, Jaiswal JK, Nylandsted J
Scientific reports 2019 Apr 30;9(1):6726
Scientific reports 2019 Apr 30;9(1):6726
Therapeutic potential of targeting S100A11 in malignant pleural mesothelioma.
Sato H, Sakaguchi M, Yamamoto H, Tomida S, Aoe K, Shien K, Yoshioka T, Namba K, Torigoe H, Soh J, Tsukuda K, Tao H, Okabe K, Miyoshi S, Pass HI, Toyooka S
Oncogenesis 2018 Jan 24;7(1):11
Oncogenesis 2018 Jan 24;7(1):11
Apigenin inhibits growth and induces apoptosis in human cholangiocarcinoma cells.
Subhasitanont P, Chokchaichamnankit D, Chiablaem K, Keeratichamroen S, Ngiwsara L, Paricharttanakul NM, Lirdprapamongkol K, Weeraphan C, Svasti J, Srisomsap C
Oncology letters 2017 Oct;14(4):4361-4371
Oncology letters 2017 Oct;14(4):4361-4371
Knockdown of BC200 RNA expression reduces cell migration and invasion by destabilizing mRNA for calcium-binding protein S100A11.
Shin H, Lee J, Kim Y, Jang S, Lee Y, Kim S, Lee Y
RNA biology 2017 Oct 3;14(10):1418-1430
RNA biology 2017 Oct 3;14(10):1418-1430
Calgizzarin (S100A11): a novel inflammatory mediator associated with disease activity of rheumatoid arthritis.
Andrés Cerezo L, Šumová B, Prajzlerová K, Veigl D, Damgaard D, Nielsen CH, Pavelka K, Vencovský J, Šenolt L
Arthritis research & therapy 2017 Apr 26;19(1):79
Arthritis research & therapy 2017 Apr 26;19(1):79
Imaging mass spectrometry for accessing molecular changes during burn wound healing.
Taverna D, Pollins AC, Sindona G, Caprioli RM, Nanney LB
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2016 Sep;24(5):775-785
Wound repair and regeneration : official publication of the Wound Healing Society [and] the European Tissue Repair Society 2016 Sep;24(5):775-785
S100A11 plays a role in homologous recombination and genome maintenance by influencing the persistence of RAD51 in DNA repair foci.
Foertsch F, Szambowska A, Weise A, Zielinski A, Schlott B, Kraft F, Mrasek K, Borgmann K, Pospiech H, Grosse F, Melle C
Cell cycle (Georgetown, Tex.) 2016 Oct 17;15(20):2766-79
Cell cycle (Georgetown, Tex.) 2016 Oct 17;15(20):2766-79
Annexin A1 Tethers Membrane Contact Sites that Mediate ER to Endosome Cholesterol Transport.
Eden ER, Sanchez-Heras E, Tsapara A, Sobota A, Levine TP, Futter CE
Developmental cell 2016 Jun 6;37(5):473-83
Developmental cell 2016 Jun 6;37(5):473-83
S100A11 is required for efficient plasma membrane repair and survival of invasive cancer cells.
Jaiswal JK, Lauritzen SP, Scheffer L, Sakaguchi M, Bunkenborg J, Simon SM, Kallunki T, Jäättelä M, Nylandsted J
Nature communications 2014 May 8;5:3795
Nature communications 2014 May 8;5:3795
S100A11 is a migration-related protein in laryngeal squamous cell carcinoma.
Wang C, Zhang Z, Li L, Zhang J, Wang J, Fan J, Jiao B, Zhao S
International journal of medical sciences 2013;10(11):1552-9
International journal of medical sciences 2013;10(11):1552-9
Disruption of the annexin A1/S100A11 complex increases the migration and clonogenic growth by dysregulating epithelial growth factor (EGF) signaling.
Poeter M, Radke S, Koese M, Hessner F, Hegemann A, Musiol A, Gerke V, Grewal T, Rescher U
Biochimica et biophysica acta 2013 Jul;1833(7):1700-11
Biochimica et biophysica acta 2013 Jul;1833(7):1700-11
S100A11 is involved in the regulation of the stability of cell cycle regulator p21(CIP1/WAF1) in human keratinocyte HaCaT cells.
Foertsch F, Teichmann N, Kob R, Hentschel J, Laubscher U, Melle C
The FEBS journal 2013 Aug;280(16):3840-53
The FEBS journal 2013 Aug;280(16):3840-53
Down-regulation of S100A11, a calcium-binding protein, in human endometrium may cause reproductive failure.
Liu XM, Ding GL, Jiang Y, Pan HJ, Zhang D, Wang TT, Zhang RJ, Shu J, Sheng JZ, Huang HF
The Journal of clinical endocrinology and metabolism 2012 Oct;97(10):3672-83
The Journal of clinical endocrinology and metabolism 2012 Oct;97(10):3672-83
Selective expression of S100A11 in lung cancer and its role in regulating proliferation of adenocarcinomas cells.
Hao J, Wang K, Yue Y, Tian T, Xu A, Hao J, Xiao X, He D
Molecular and cellular biochemistry 2012 Jan;359(1-2):323-32
Molecular and cellular biochemistry 2012 Jan;359(1-2):323-32
Tissue-based proteomics reveals FXYD3, S100A11 and GSTM3 as novel markers for regional lymph node metastasis in colon cancer.
Meding S, Balluff B, Elsner M, Schöne C, Rauser S, Nitsche U, Maak M, Schäfer A, Hauck SM, Ueffing M, Langer R, Höfler H, Friess H, Rosenberg R, Walch A
The Journal of pathology 2012 Dec;228(4):459-70
The Journal of pathology 2012 Dec;228(4):459-70
S100A11 mediates hypoxia-induced mitogenic factor (HIMF)-induced smooth muscle cell migration, vesicular exocytosis, and nuclear activation.
Fan C, Fu Z, Su Q, Angelini DJ, Van Eyk J, Johns RA
Molecular & cellular proteomics : MCP 2011 Mar;10(3):M110.000901
Molecular & cellular proteomics : MCP 2011 Mar;10(3):M110.000901
LRRC4 inhibits the proliferation of human glioma cells by modulating the expression of STMN1 and microtubule polymerization.
Wang R, Wang Z, Yang J, Liu X, Wang L, Guo X, Zeng F, Wu M, Li G
Journal of cellular biochemistry 2011 Dec;112(12):3621-9
Journal of cellular biochemistry 2011 Dec;112(12):3621-9
Ca2+-binding protein S100A11: a novel diagnostic marker for breast carcinoma.
Liu XG, Wang XP, Li WF, Yang S, Zhou X, Li SJ, Li XJ, Hao DY, Fan ZM
Oncology reports 2010 May;23(5):1301-8
Oncology reports 2010 May;23(5):1301-8
DNA damage-induced translocation of S100A11 into the nucleus regulates cell proliferation.
Gorsler T, Murzik U, Ulbricht T, Hentschel J, Hemmerich P, Melle C
BMC cell biology 2010 Dec 17;11:100
BMC cell biology 2010 Dec 17;11:100
Novel proteins regulated by mTOR in subependymal giant cell astrocytomas of patients with tuberous sclerosis complex and new therapeutic implications.
Tyburczy ME, Kotulska K, Pokarowski P, Mieczkowski J, Kucharska J, Grajkowska W, Roszkowski M, Jozwiak S, Kaminska B
The American journal of pathology 2010 Apr;176(4):1878-90
The American journal of pathology 2010 Apr;176(4):1878-90
Regulation of cellular actin architecture by S100A10.
Jung MJ, Murzik U, Wehder L, Hemmerich P, Melle C
Experimental cell research 2010 Apr 15;316(7):1234-40
Experimental cell research 2010 Apr 15;316(7):1234-40
Proteomics-based identification of two novel direct targets of hypoxia-inducible factor-1 and their potential roles in migration/invasion of cancer cells.
Liao SH, Zhao XY, Han YH, Zhang J, Wang LS, Xia L, Zhao KW, Zheng Y, Guo M, Chen GQ
Proteomics 2009 Aug;9(15):3901-12
Proteomics 2009 Aug;9(15):3901-12
Comparative proteomic analysis of differentially expressed proteins in human pancreatic cancer tissue.
Chen JH, Ni RZ, Xiao MB, Guo JG, Zhou JW
Hepatobiliary & pancreatic diseases international : HBPD INT 2009 Apr;8(2):193-200
Hepatobiliary & pancreatic diseases international : HBPD INT 2009 Apr;8(2):193-200
Colon-derived liver metastasis, colorectal carcinoma, and hepatocellular carcinoma can be discriminated by the Ca(2+)-binding proteins S100A6 and S100A11.
Melle C, Ernst G, Schimmel B, Bleul A, von Eggeling F
PloS one 2008;3(12):e3767
PloS one 2008;3(12):e3767
Th2 cytokines act on S100/A11 to downregulate keratinocyte differentiation.
Howell MD, Fairchild HR, Kim BE, Bin L, Boguniewicz M, Redzic JS, Hansen KC, Leung DY
The Journal of investigative dermatology 2008 Sep;128(9):2248-58
The Journal of investigative dermatology 2008 Sep;128(9):2248-58
Colorectal cancer progression correlates with upregulation of S100A11 expression in tumor tissues.
Wang G, Wang X, Wang S, Song H, Sun H, Yuan W, Cao B, Bai J, Fu S
International journal of colorectal disease 2008 Jul;23(7):675-82
International journal of colorectal disease 2008 Jul;23(7):675-82
Rad54B targeting to DNA double-strand break repair sites requires complex formation with S100A11.
Murzik U, Hemmerich P, Weidtkamp-Peters S, Ulbricht T, Bussen W, Hentschel J, von Eggeling F, Melle C
Molecular biology of the cell 2008 Jul;19(7):2926-35
Molecular biology of the cell 2008 Jul;19(7):2926-35
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Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- PC-3 cells were subjected to SDS PAGE followed by western blot with 10237-1-AP(S100A11 antibody) at dilution of 1:2000
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- IP Result of anti-S100A11 (IP:10237-1-AP, 3ug; Detection:10237-1-AP 1:1000) with PC-3 cells lysate 1000ug.
- Sample type
- cell line
Supportive validation
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- Immunohistochemical of paraffin-embedded human breast cancer using 10237-1-AP(S100A11 antibody) at dilution of 1:50 (under 10x lens)
- Sample type
- tissue
- Submitted by
- Proteintech Group (provider)
- Main image
- Experimental details
- The S100A11 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human S100A11. This antibody recognizes human,mouse,rat antigen. The S100A11 antibody has been validated for the following applications: ELISA, WB, IHC, IP analysis.
