CABT-BL4965

KCNN3 antibody from Creative Diagnostics
hSK3, KCa2.3, SKCA3
Western blot
Recommended by provider
Immunohistochemistry
Recommended by provider

Antibody data

Product number
CABT-BL4965
Provider
Creative Diagnostics
Product name
Anti-KCNN3 (C-terminal) polyclonal antibody
Provider product page
Creative Diagnostics - CABT-BL4965
Antibody type
Polyclonal
Description
Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Reactivity
Human, Mouse, Rat
Host
Rabbit
Conjugate
Unconjugated
Isotype
IgG
Vial size
100 _l
Storage
Store at 4°C short term (1-2 weeks). Aliquot and store at -20°C (add glycerol to a final volume of 40% for extra stability). Avoid repeated freeze/thaw cycles.
Provider Type Product Number
- No reagents -