NBP2-34714AF350

antibody from Novus Biologicals
Targeting: CD1B CD1
Provider product page for NBP2-34714AF350
ELISA
Immunocytochemistry
Immunohistochemistry
Flow cytometry

Antibody data

Product number
NBP2-34714AF350 - Provider product page
Provider
Novus Biologicals
Product name
Mouse Monoclonal CD1b Antibody
Antibody type
Monoclonal
Description
Protein A purified. The mouse monoclonal antibody recognizes CD1b, a 44kDa type I glycoprotein associated with beta2-microglobulin. It is expressed on dendritic cells, Langerhans cells, thymocytes, and T acute lymphoblastic leukemia cells. The CD1 multigene family encodes five forms of the CD1 T-cell surface glycoprotein in human, designated CD1A, 1B, 1C, 1D and 1E. CD1, a type 1 membrane protein, has structural similarity to the MHC class I antigen and has been shown to present lipid antigens for recognition by T lymphocytes. Constitutive endocytosis of CD1B molecules and the differential sorting of MHC class II from lysosomes separate peptide- and lipid antigen-presenting molecules during dendritic cell maturation. CD1B is also expressed in interdigitating cells.
Reactivity
Human
Host
Mouse
Conjugate
Blue dye
Isotype
IgG
Vial size
0.1 ml
Storage
Store at 4C in the dark.
CD1B protein structure - NBP2-34714AF350 shown in red.