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ImmunocytochemistryAntibody data
- Antibody Data
- Antigen structure
- References [1]
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- Product number
- 326102 - Provider product page
- Provider
- BioLegend
- Product name
- Purified anti-human CD229 (Ly-9)
- Antibody type
- Monoclonal
- Antigen
- 300.19 cell line transfected with the CD229 full-length DNA
- Description
- CD229 is a 100-120 kD glycoprotein. It is a member of the SLAM family, a CD2 subset of the Ig superfamily, known as Ly9 or SLAMF3. CD229 is expressed on T cells, B cells, NK cells, and thymocytes. It functions as a homophilic adhesion molecule through binding to CD229 itself. The cytoplasmic tail of CD229 binds to SAP and Grb2 proteins. CD229 is involved in enhancing T cell activation and Th2 polarization. HLy9.1.25 antibody recognizes epitope A in the first Ig domain of Ly9 molecule.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- The antibody solution should be stored undiluted at 4°C.
Submitted references Increased expression of SLAM receptors SLAMF3 and SLAMF6 in systemic lupus erythematosus T lymphocytes promotes Th17 differentiation.
Chatterjee M, Rauen T, Kis-Toth K, Kyttaris VC, Hedrich CM, Terhorst C, Tsokos GC
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1206-12
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 1;188(3):1206-12
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