BS8337

antibody from Bioworld Technology, Inc
Targeting: MYOG bHLHc3, MYF4
Provider product page for BS8337
Western blot
Immunohistochemistry

Antibody data

Product number
BS8337 - Provider product page
Provider
Bioworld Technology, Inc
Product name
MYOG polyclonal antibody
Antibody type
Polyclonal
Antigen
Recombinant full length Human MYOG.
Description
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH) proteins known to play an important role in the regulation of muscle cell development includes Myo D, myogenin, Myf-5 and Myf-6 (also designated MRF-4 or herculin). Of interest, most muscle cells express either Myo D or Myf-5 in the committed state, but when induced to differentiate, all turn on expression of myogenin. Myo D transcription factors form heterodimers with products of a more widely expressed family of bHLH genes, the E family, which consists of at least three distinct genes: E2A, IF2 and HEB. Myo D-E heterodimers bind avidly to consensus (CANNTG) E box target sites that are functionally important elements in the upstream regulatory sequences of many muscle-specific terminal differentiation genes.
Reactivity
Human, Mouse, Rat
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
MYOG protein structure - BS8337 shown in red.