ZNF124

This gene encodes a protein with an amino-terminal KRAB-A box and multiple repeated Kruppel-type (C2H2) zinc finger motifs at its carboxy terminus. The encoded protein may function as a transcription factor. Expression of this gene is increased after vascular endothelial growth factor (VEGF) stimulation in human leukemia cell lines and results in inhibition of apoptotic cell death induced by irradiation or exposure to etoposide. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Jul 2014]

Description

Zinc finger protein 124

Tissue specificity

Tissue enhanced (salivary gland)

Subcell location

Nucleoplasm, Nuclear membrane

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Transcription factors

Chromosome

1 (247121975 - 247172016)

Ensembl ID

ENSG00000196418  (ver. 103.38)

Orthologs

-

UniProt

Q15973

neXtProt

NX_Q15973

Human splice variants

Protein structure