Tissue expression
Cell line expression
Protein structure

TNFRSF18

TNF receptor superfamily member 18
AITR, CD357, GITR 
This gene encodes a member of the TNF-receptor superfamily. The encoded receptor has been shown to have increased expression upon T-cell activation, and it is thought to play a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. Knockout studies in mice also suggest the role of this receptor is in the regulation of CD3-driven T-cell activation and programmed cell death. Three alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq, Feb 2011]
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1267 antibodies from 43 providers.

Antibody properties

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AntibodyRefsTypeWBELICCIPIHCFC
Invitrogen Antibodies
66 antibodies
R&D Systems
38 antibodies
Novus Biologicals
180 antibodies
Cell Signaling Technology, Inc
6 antibodies
Biorbyt
71 antibodies
GeneTex
10 antibodies
OriGene
27 antibodies
NSJ Bioreagents
4 antibodies
Bethyl Laboratories
1 antibody
antibodies-online
192 antibodies
Enzo Life Sciences
3 antibodies
Abnova Corporation
16 antibodies
Acris Antibodies GmbH
11 antibodies
Cusabio Biotech Co., Ltd
4 antibodies
Aladdin Scientific Corporation
1 antibody
NovoPro Bioscience Inc.
1 antibody
BioLegend
34 antibodies
Aviva Systems Biology
8 antibodies
Boster Biological Technology
3 antibodies
ProSci
16 antibodies
Abbkine Scientific Co.Ltd.
1 antibody
St John's Laboratory
2 antibodies
Abbiotec
1 antibody
Atlas Antibodies
1 antibody
Miltenyi Biotec
34 antibodies
Absolute Antibody
17 antibodies
Proteintech Group
6 antibodies
Creative Diagnostics
12 antibodies
Creative Biolabs
275 antibodies
MyBioSource
4 antibodies
eBioscience, An Affymetrix Company
6 antibodies
Abiocode, Inc.
1 antibody
RayBiotech, Inc.
1 antibody
MilliporeSigma / Merck KGaA
4 antibodies
Leading Biology
3 antibodies
United States Biological
16 antibodies
Abbexa
9 antibodies
GenWay
2 antibodies
Abgent
1 antibody
EMD Millipore
1 antibody