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Cell line expression
Protein structure
CNOT7
CCR4-NOT transcription complex subunit 7CAF1
The protein encoded by this gene binds to an anti-proliferative protein, B-cell translocation protein 1, which negatively regulates cell proliferation. Binding of the two proteins, which is driven by phosphorylation of the anti-proliferative protein, causes signaling events in cell division that lead to changes in cell proliferation associated with cell-cell contact. The encoded protein downregulates the innate immune response and therefore provides a therapeutic target for enhancing its antimicrobial activity against foreign agents. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and X. [provided by RefSeq, Apr 2016]
Top validated antibodies |
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| antibodies-online |  ABIN951587 |
2 references | Polyclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | H00029883-M01 |
5 references | Monoclonal |
WB
EL
ICC
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| Abnova Corporation | H00029883-M01 |
3 references | Monoclonal |
WB
EL
ICC
|
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| Proteintech Group | 14102-1-AP |
4 references | Polyclonal |
WB
EL
IP
|
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| GeneTex | GTX118241 |
3 references | Polyclonal |
WB
ICC
IHC
|
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