AMM00174G

antibody from Leading Biology

Targeting: MCAM CD146, HEMCAM, MelCAM, METCAM, MUC18

Western blot (Recommended by provider)

Immunoprecipitation (Recommended by provider)

Immunohistochemistry (Recommended by provider)

Flow cytometry (Recommended by provider)

Antibody Data

Product number

AMM00174G

Provider

Leading Biology

Product name

MUC18 / CD146 / MCAM (Melanoma Cell Adhesion Molecule) Antibody - With BSA and Azide

Antibody type

Monoclonal

Description

The human Mel-CAM gene maps to chromosome 11q23 and encodes a trans-membrane glycoprotein, also designated MCAM, MUC 18 or CD146, that belongs to the immunoglobulin superfamily and functions as a Ca2+-independent cell adhesion molecule. Mel-CAM expression is restricted to advanced primary and metastatic melanomas and to cell lines of the neuroectodermal lineage, but not normal melanocytes. Mel-CAM is found on 80% of advanced primary human melanomas and correlates well with development of metastatic disease.

Reactivity

Human

Host

Mouse

Isotype

IgG

Antibody clone number

OJ79c

Storage

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.