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- Product number
- ABIN953495 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Melanocortin 2 Receptor Accessory Protein (MRAP) (AA 14-44), (N-Term) antibody
- Antibody type
- Polyclonal
- Description
- Purified through a Protein A column followed by peptide affinity purification
- Reactivity
- Human
- Host
- Rabbit
- Epitope
- AA 14-44, N-Term
- Vial size
- 0.4 mL
- Storage
- Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer.
- Handling
- Avoid repeated freezing and thawing.
Submitted references Isolated Addison's disease is unlikely to be caused by mutations in MC2R, MRAP or STAR, three genes responsible for familial glucocorticoid deficiency.
Distinct melanocortin 2 receptor accessory protein domains are required for melanocortin 2 receptor interaction and promotion of receptor trafficking.
MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family.
Dias RP, Chan LF, Metherell LA, Pearce SH, Clark AJ
European journal of endocrinology 2010 Feb;162(2):357-9
European journal of endocrinology 2010 Feb;162(2):357-9
Distinct melanocortin 2 receptor accessory protein domains are required for melanocortin 2 receptor interaction and promotion of receptor trafficking.
Webb TR, Chan L, Cooray SN, Cheetham ME, Chapple JP, Clark AJ
Endocrinology 2009 Feb;150(2):720-6
Endocrinology 2009 Feb;150(2):720-6
MRAP and MRAP2 are bidirectional regulators of the melanocortin receptor family.
Chan LF, Webb TR, Chung TT, Meimaridou E, Cooray SN, Guasti L, Chapple JP, Egertová M, Elphick MR, Cheetham ME, Metherell LA, Clark AJ
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 14;106(15):6146-51
Proceedings of the National Academy of Sciences of the United States of America 2009 Apr 14;106(15):6146-51
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Supportive validation
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Supportive validation
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- IHC
Supportive validation
- Submitted by
- antibodies-online (provider)
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- Experimental details
- FACS
