RGS11

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]

Description

Regulator of G protein signaling 11

Tissue specificity

Tissue enhanced (brain, pituitary gland)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins

Chromosome

16 (268301 - 275980)

Ensembl ID

ENSG00000076344  (ver. 103.38)

Orthologs

Mouse Rgs11: ENSMUSG00000024186

UniProt

O94810

neXtProt

NX_O94810

Human splice variants
Mouse splice variants

Protein structure