FXYD3

This gene belongs to a small family of FXYD-domain containing regulators of Na+/K+ ATPases which share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD, and containing 7 invariant and 6 highly conserved amino acids. This gene encodes a cell membrane protein that may regulate the function of ion-pumps and ion-channels. This gene may also play a role in tumor progression. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

Description

FXYD domain containing ion transport regulator 3

Tissue specificity

Tissue enhanced (intestine)

Subcell location

Nucleoplasm, Plasma membrane

Predicted location

Intracellular, Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Transporters

Chromosome

19 (35115879 - 35124324)

Ensembl ID

ENSG00000089356  (ver. 103.38)

Orthologs

-

UniProt

Q14802

neXtProt

NX_Q14802

Human splice variants

Protein structure