SORCS2

This gene encodes one family member of vacuolar protein sorting 10 (VPS10) domain-containing receptor proteins. The VPS10 domain name comes from the yeast carboxypeptidase Y sorting receptor Vps10 protein. Members of this gene family are large with many exons but the CDS lengths are usually less than 3700 nt. Very large introns typically separate the exons encoding the VPS10 domain; the remaining exons are separated by much smaller-sized introns. These genes are strongly expressed in the central nervous system. [provided by RefSeq, Jul 2008]

Description

Sortilin related VPS10 domain containing receptor 2

Tissue specificity

Tissue enhanced (brain)

Subcell location

Vesicles, Cytosol

Predicted location

Membrane

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

4 (7192538 - 7742836)

Ensembl ID

ENSG00000184985  (ver. 103.38)

Orthologs

Mouse Sorcs2: ENSMUSG00000029093

UniProt

Q96PQ0

neXtProt

NX_Q96PQ0

Human splice variants
Mouse splice variants

Protein structure