PURG

The exact function of this gene is not known, however, its encoded product is highly similar to purine-rich element binding protein A. The latter is a DNA-binding protein which binds preferentially to the single strand of the purine-rich element termed PUR, and has been implicated in the control of both DNA replication and transcription. This gene lies in close proximity to the Werner syndrome gene, but on the opposite strand, on chromosome 8p11. [provided by RefSeq, Apr 2016]

Description

Purine rich element binding protein G

Tissue specificity

Tissue enriched (brain)

Subcell location

Nucleoplasm, Nucleoli, Plasma membrane

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Transcription factors

Chromosome

8 (30995802 - 31033715)

Ensembl ID

ENSG00000172733  (ver. 103.38)

Orthologs

Mouse Purg: ENSMUSG00000049184

UniProt

Q9UJV8

neXtProt

NX_Q9UJV8

Human splice variants
Mouse splice variants

Protein structure