abx030021

antibody from Abbexa

Targeting: LRR1 LRR-1, MGC20689, PPIL5

No application information provided.

Antibody Data

Product number

abx030021

Provider

Abbexa

Product name

Leucine Rich Repeat Protein 1 / PPIL5 (LRR1) Antibody

Antibody type

Polyclonal

Description

The protein encoded by this gene contains a leucine-rich repeat (LRR). It specifically interacts with TNFRSF9/4-1BB, a member of the tumor necrosis factor receptor (TNFR) superfamily. Overexpression of this gene suppresses the activation of NF-kappa B induced by TNFRSF9 or TNF receptor-associated factor 2 (TRAF2), which suggests that this protein is a negative regulator of TNFRSF9-mediated signaling cascades. At least three alternatively spliced transcript variants encoding distinct isoforms have been observed.

Reactivity

Human

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

80 µl

Storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.