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Western blotAntibody data
- Antibody Data
- Antigen structure
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- Validations
- Western blot [1]
- Flow cytometry [1]
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- Product number
- 10-4166 - Provider product page
- Provider
- ABEOMICS Inc.
- Product name
- Anti-IL-36R Antibody
- Antibody type
- Monoclonal
- Description
- IL-36R is a member of the IL-1 receptor family that has been associated with various inflammation-associated diseases. Ligands binding to IL-36R subsequently recruit the IL-1RAcP (IL-1 Receptor Accessory Protein) forming a heterodimeric signaling complex. The latter is also used by IL-1Alpha and IL-1Beta. IL-36R is expressed by different immune cells, including Dendritic Cells, microglia and other myeloid cells. IL-36 stimulation of DC leads to the production of several cytokines by DC, including TNF-a, IL-1, IL-12, and IL-23. This interaction also enhances the expression of MHC class 2 and co-stimulatory molecules.
- Reactivity
- Human
- Host
- Mouse
- Conjugate
- Unconjugated
- Antigen sequence
A partial length recombinant IL-36R
protein (amino acids 1-203) was us
ed as the immunogen for this antibo
dy.- Isotype
- IgG
- Antibody clone number
- ABM47A2
- Vial size
- 100 µg
- Concentration
- 0.5 mg/ml
- Storage
- Store the antibody at 4°C, stable for 6 months. For long-term storage, store at -20°C. Avoid repeat freez thawing
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Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Western blot analysis of IL-36R. Anti-IL-36R antibody (Clone: ABM47A2) was tested at 2 µg/ml on human Small Intestine lysate.
- Protocol
- Protocol
Supportive validation
- Submitted by
- ABEOMICS Inc. (provider)
- Main image
- Experimental details
- Intracellular Flowcytometric analysis of IL-36R in K562 cells using 0.5 µg/10^6 Cells of IL-36R antibody (Clone: ABM47A2). Green represent isotype control and red represent Anti- IL36R antibody. (ABEOMICS 10-4166). Goat Anti-Mouse PE conjugated was used as secondary antibody.
- Protocol
- Protocol
