Explore
Validate
Learn
ELISA
ImmunohistochemistryAntibody data
- Antibody Data
- Antigen structure
- References [74]
- Comments [0]
- Validations
- Immunohistochemistry [3]
- Flow cytometry [1]
Submit
Validation data
Reference
Comment
Report error
- Product number
- DDX0362P-100 - Provider product page
- Provider
- Novus Biologicals
- Product name
- Rat Monoclonal Langerin/CD207 Antibody
- Antibody type
- Monoclonal
- Description
- Ion exchange chromatography.
- Reactivity
- Human, Mouse, Rat, Porcine
- Host
- Rat
- Isotype
- IgG
- Vial size
- 0.1 mg
- Concentration
- 0.5 mg/ml
- Storage
- Store at -20C. Avoid freeze-thaw cycles.
Submitted references Reduction in Human Epidermal Langerhans Cells with Age Is Associated with Decline in CXCL14-Mediated Recruitment of CD14(+) Monocytes.
BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis.
Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization.
Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche.
Keratinocyte-derived TGFβ is not required to maintain skin immune homeostasis.
Topically applied azaphenothiazines inhibit experimental psoriasis in mice.
Topically applied azaphenothiazines inhibit contact sensitivity to oxazolone in mice.
Sequential BMP7/TGF-β1 signaling and microbiota instruct mucosal Langerhans cell differentiation.
MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation.
Epithelium Expressing the E7 Oncoprotein of HPV16 Attracts Immune-Modulatory Dendritic Cells to the Skin and Suppresses Their Antigen-Processing Capacity.
Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells.
Immune Reactions against Gene Gun Vaccines Are Differentially Modulated by Distinct Dendritic Cell Subsets in the Skin.
Langerhans cell homeostasis and activation is altered in hyperplastic human papillomavirus type 16 E7 expressing epidermis.
Activated Conventional T-Cells Are Present in Langerhans Cell Histiocytosis Lesions Despite the Presence of Immune Suppressive Cytokines.
Langerhans cells in the sebaceous gland of the murine skin.
The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells.
Commensal-dendritic-cell interaction specifies a unique protective skin immune signature.
Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance.
Anatomical distribution analysis reveals lack of Langerin+ dermal dendritic cells in footpads and tail of C57BL/6 mice.
Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells.
Hyaluronan digestion controls DC migration from the skin.
Antigen-presenting cells are stratified within normal human corneas and are rapidly mobilized during ex vivo viral infection.
Second-generation Langerhans cells originating from epidermal precursors are essential for CD8+ T cell priming.
Fcγ receptor III and Fcγ receptor IV on macrophages drive autoimmune valvular carditis in mice.
Comparative histology and immunohistochemistry of porcine versus human skin.
Isolation, processing and analysis of murine gingival cells.
Langerhans cell homeostasis in mice is dependent on mTORC1 but not mTORC2 function.
Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo.
Deletion of microRNA miR-223 increases Langerhans cell cross-presentation.
Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays.
Human papillomavirus type 8 interferes with a novel C/EBPβ-mediated mechanism of keratinocyte CCL20 chemokine expression and Langerhans cell migration.
Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.
Aging affects epidermal Langerhans cell development and function and alters their miRNA gene expression profile.
Age-related changes in expression and function of Toll-like receptors in human skin.
Langerhans cells require MyD88-dependent signals for Candida albicans response but not for contact hypersensitivity or migration.
Langerhans cells down-regulate inflammation-driven alveolar bone loss.
Skin langerin+ dendritic cells transport intradermally injected anti-DEC-205 antibodies but are not essential for subsequent cytotoxic CD8+ T cell responses.
CD64 expression distinguishes monocyte-derived and conventional dendritic cells and reveals their distinct role during intramuscular immunization.
Characterization of resident and migratory dendritic cells in human lymph nodes.
Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization.
Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.
Phenotypic localization of distinct DC subsets in mouse Peyer Patch.
Calcitonin gene-related peptide is an important regulator of cutaneous immunity: effect on dendritic cell and T cell functions.
Characterization of dendritic cells subpopulations in skin and afferent lymph in the swine model.
Langerin+ dermal dendritic cells are critical for CD8+ T cell activation and IgH γ-1 class switching in response to gene gun vaccines.
The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.
Acute ablation of Langerhans cells enhances skin immune responses.
Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.
CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells.
Functional redundancy of Langerhans cells and Langerin+ dermal dendritic cells in contact hypersensitivity.
Herpes simplex virus type 2 enhances HIV-1 susceptibility by affecting Langerhans cell function.
Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network.
The lymph vessel network in mouse skin visualised with antibodies against the hyaluronan receptor LYVE-1.
Inefficient presentation of tumor-derived antigen by tumor-infiltrating dendritic cells.
Expression of langerin/CD207 reveals dendritic cell heterogeneity between inbred mouse strains.
Epidermal and dermal dendritic cells display differential activation and migratory behavior while sharing the ability to stimulate CD4+ T cell proliferation in vivo.
Epidermal and dermal dendritic cells display differential activation and migratory behavior while sharing the ability to stimulate CD4+ T cell proliferation in vivo.
Langerhans cells in porcine skin.
Langerhans cells and lymph node dendritic cells express the tight junction component claudin-1.
Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells.
Epidermal langerhans cells are dispensable for humoral and cell-mediated immunity elicited by gene gun immunization.
Epidermal langerhans cells are dispensable for humoral and cell-mediated immunity elicited by gene gun immunization.
Identification of a novel population of Langerin+ dendritic cells.
The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells.
Peroxisome proliferator-activated receptor-alpha activation inhibits Langerhans cell function.
Peroxisome proliferator-activated receptor-alpha activation inhibits Langerhans cell function.
Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes.
Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells.
Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function.
Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity.
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Hasegawa T, Feng Z, Yan Z, Ngo KH, Hosoi J, Demehri S
The Journal of investigative dermatology 2020 Jul;140(7):1327-1334
The Journal of investigative dermatology 2020 Jul;140(7):1327-1334
BRAF V600E and Pten deletion in mice produces a histiocytic disorder with features of Langerhans cell histiocytosis.
Nelson DS, Marano RL, Joo Y, Tian SY, Patel B, Kaplan DH, Shlomchik MJ, Stevenson K, Bronson RT, Rollins BJ
PloS one 2019;14(9):e0222400
PloS one 2019;14(9):e0222400
Neutrophil Recruitment to Noninvasive MRSA at the Stratum Corneum of Human Skin Mediates Transient Colonization.
Schulz A, Jiang L, de Vor L, Ehrström M, Wermeling F, Eidsmo L, Melican K
Cell reports 2019 Oct 29;29(5):1074-1081.e5
Cell reports 2019 Oct 29;29(5):1074-1081.e5
Stellate Cells, Hepatocytes, and Endothelial Cells Imprint the Kupffer Cell Identity on Monocytes Colonizing the Liver Macrophage Niche.
Bonnardel J, T'Jonck W, Gaublomme D, Browaeys R, Scott CL, Martens L, Vanneste B, De Prijck S, Nedospasov SA, Kremer A, Van Hamme E, Borghgraef P, Toussaint W, De Bleser P, Mannaerts I, Beschin A, van Grunsven LA, Lambrecht BN, Taghon T, Lippens S, Elewaut D, Saeys Y, Guilliams M
Immunity 2019 Oct 15;51(4):638-654.e9
Immunity 2019 Oct 15;51(4):638-654.e9
Keratinocyte-derived TGFβ is not required to maintain skin immune homeostasis.
Yang Y, Zenke Y, Hirai T, Kaplan DH
Journal of dermatological science 2019 May;94(2):290-297
Journal of dermatological science 2019 May;94(2):290-297
Topically applied azaphenothiazines inhibit experimental psoriasis in mice.
Artym J, Kocięba M, Zaczyńska E, Kochanowska I, Zimecki M, Kałas W, Fiedorowicz A, Pawlak A, Strządała L, Jeleń M, Morak-Młodawska B, Pluta K, Kaleta-Kuratewicz K, Madej JP, Kuropka P, Kuryszko J
International immunopharmacology 2018 Jun;59:276-286
International immunopharmacology 2018 Jun;59:276-286
Topically applied azaphenothiazines inhibit contact sensitivity to oxazolone in mice.
Artym J, Kocięba M, Zaczyńska E, Zimecki M, Jeleń M, Morak-Młodawska B, Pluta K, Kaleta-Kuratewicz K, Madej JP, Kuropka P, Kuryszko J
Histology and histopathology 2018 Feb;33(2):223-236
Histology and histopathology 2018 Feb;33(2):223-236
Sequential BMP7/TGF-β1 signaling and microbiota instruct mucosal Langerhans cell differentiation.
Capucha T, Koren N, Nassar M, Heyman O, Nir T, Levy M, Zilberman-Schapira G, Zelentova K, Eli-Berchoer L, Zenke M, Hieronymus T, Wilensky A, Bercovier H, Elinav E, Clausen BE, Hovav AH
The Journal of experimental medicine 2018 Feb 5;215(2):481-500
The Journal of experimental medicine 2018 Feb 5;215(2):481-500
MAIT cells reside in the female genital mucosa and are biased towards IL-17 and IL-22 production in response to bacterial stimulation.
Gibbs A, Leeansyah E, Introini A, Paquin-Proulx D, Hasselrot K, Andersson E, Broliden K, Sandberg JK, Tjernlund A
Mucosal immunology 2017 Jan;10(1):35-45
Mucosal immunology 2017 Jan;10(1):35-45
Epithelium Expressing the E7 Oncoprotein of HPV16 Attracts Immune-Modulatory Dendritic Cells to the Skin and Suppresses Their Antigen-Processing Capacity.
Chandra J, Miao Y, Romoff N, Frazer IH
PloS one 2016;11(3):e0152886
PloS one 2016;11(3):e0152886
Deletion of Wiskott-Aldrich syndrome protein triggers Rac2 activity and increased cross-presentation by dendritic cells.
Baptista MA, Keszei M, Oliveira M, Sunahara KK, Andersson J, Dahlberg CI, Worth AJ, Liedén A, Kuo IC, Wallin RP, Snapper SB, Eidsmo L, Scheynius A, Karlsson MC, Bouma G, Burns SO, Forsell MN, Thrasher AJ, Nylén S, Westerberg LS
Nature communications 2016 Jul 18;7:12175
Nature communications 2016 Jul 18;7:12175
Immune Reactions against Gene Gun Vaccines Are Differentially Modulated by Distinct Dendritic Cell Subsets in the Skin.
Weber CS, Hainz K, Deressa T, Strandt H, Florindo Pinheiro D, Mittermair R, Pizarro Pesado J, Thalhamer J, Hammerl P, Stoecklinger A
PloS one 2015;10(6):e0128722
PloS one 2015;10(6):e0128722
Langerhans cell homeostasis and activation is altered in hyperplastic human papillomavirus type 16 E7 expressing epidermis.
Abd Warif NM, Stoitzner P, Leggatt GR, Mattarollo SR, Frazer IH, Hibma MH
PloS one 2015;10(5):e0127155
PloS one 2015;10(5):e0127155
Activated Conventional T-Cells Are Present in Langerhans Cell Histiocytosis Lesions Despite the Presence of Immune Suppressive Cytokines.
Quispel WT, Stegehuis-Kamp JA, Santos SJ, Egeler RM, van Halteren AG
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2015 Oct;35(10):831-9
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2015 Oct;35(10):831-9
Langerhans cells in the sebaceous gland of the murine skin.
Haid B, Schlögl DE, Hermann M, Tripp CH, Stoitzner P, Romani N, Flacher V
Experimental dermatology 2015 Nov;24(11):899-901
Experimental dermatology 2015 Nov;24(11):899-901
The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells.
Sparber F, Tripp CH, Komenda K, Scheffler JM, Clausen BE, Huber LA, Romani N, Stoitzner P
The Journal of investigative dermatology 2015 Jan;135(1):119-129
The Journal of investigative dermatology 2015 Jan;135(1):119-129
Commensal-dendritic-cell interaction specifies a unique protective skin immune signature.
Naik S, Bouladoux N, Linehan JL, Han SJ, Harrison OJ, Wilhelm C, Conlan S, Himmelfarb S, Byrd AL, Deming C, Quinones M, Brenchley JM, Kong HH, Tussiwand R, Murphy KM, Merad M, Segre JA, Belkaid Y
Nature 2015 Apr 2;520(7545):104-8
Nature 2015 Apr 2;520(7545):104-8
Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance.
Flacher V, Tripp CH, Mairhofer DG, Steinman RM, Stoitzner P, Idoyaga J, Romani N
EMBO molecular medicine 2014 Sep;6(9):1191-204
EMBO molecular medicine 2014 Sep;6(9):1191-204
Anatomical distribution analysis reveals lack of Langerin+ dermal dendritic cells in footpads and tail of C57BL/6 mice.
Voisin B, Mairhofer DG, Chen S, Stoitzner P, Mueller CG, Flacher V
Experimental dermatology 2014 May;23(5):354-6
Experimental dermatology 2014 May;23(5):354-6
Flt3L dependence helps define an uncharacterized subset of murine cutaneous dendritic cells.
Mollah SA, Dobrin JS, Feder RE, Tse SW, Matos IG, Cheong C, Steinman RM, Anandasabapathy N
The Journal of investigative dermatology 2014 May;134(5):1265-1275
The Journal of investigative dermatology 2014 May;134(5):1265-1275
Hyaluronan digestion controls DC migration from the skin.
Muto J, Morioka Y, Yamasaki K, Kim M, Garcia A, Carlin AF, Varki A, Gallo RL
The Journal of clinical investigation 2014 Mar;124(3):1309-19
The Journal of clinical investigation 2014 Mar;124(3):1309-19
Antigen-presenting cells are stratified within normal human corneas and are rapidly mobilized during ex vivo viral infection.
Knickelbein JE, Buela KA, Hendricks RL
Investigative ophthalmology & visual science 2014 Feb 24;55(2):1118-23
Investigative ophthalmology & visual science 2014 Feb 24;55(2):1118-23
Second-generation Langerhans cells originating from epidermal precursors are essential for CD8+ T cell priming.
Elnekave M, Furmanov K, Shaul Y, Capucha T, Eli-Berchoer L, Zelentsova K, Clausen BE, Hovav AH
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 15;192(4):1395-403
Journal of immunology (Baltimore, Md. : 1950) 2014 Feb 15;192(4):1395-403
Fcγ receptor III and Fcγ receptor IV on macrophages drive autoimmune valvular carditis in mice.
Hobday PM, Auger JL, Schuneman GR, Haasken S, Verbeek JS, Binstadt BA
Arthritis & rheumatology (Hoboken, N.J.) 2014 Apr;66(4):852-62
Arthritis & rheumatology (Hoboken, N.J.) 2014 Apr;66(4):852-62
Comparative histology and immunohistochemistry of porcine versus human skin.
Debeer S, Le Luduec JB, Kaiserlian D, Laurent P, Nicolas JF, Dubois B, Kanitakis J
European journal of dermatology : EJD 2013 Jul-Aug;23(4):456-66
European journal of dermatology : EJD 2013 Jul-Aug;23(4):456-66
Isolation, processing and analysis of murine gingival cells.
Mizraji G, Segev H, Wilensky A, Hovav AH
Journal of visualized experiments : JoVE 2013 Jul 2;(77):e50388
Journal of visualized experiments : JoVE 2013 Jul 2;(77):e50388
Langerhans cell homeostasis in mice is dependent on mTORC1 but not mTORC2 function.
Kellersch B, Brocker T
Blood 2013 Jan 10;121(2):298-307
Blood 2013 Jan 10;121(2):298-307
Rho-family GTPase Cdc42 controls migration of Langerhans cells in vivo.
Luckashenak N, Wähe A, Breit K, Brakebusch C, Brocker T
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):27-35
Journal of immunology (Baltimore, Md. : 1950) 2013 Jan 1;190(1):27-35
Deletion of microRNA miR-223 increases Langerhans cell cross-presentation.
Mi QS, Xu YP, Wang H, Qi RQ, Dong Z, Zhou L
The international journal of biochemistry & cell biology 2013 Feb;45(2):395-400
The international journal of biochemistry & cell biology 2013 Feb;45(2):395-400
Langerin negative dendritic cells promote potent CD8+ T-cell priming by skin delivery of live adenovirus vaccine microneedle arrays.
Bachy V, Hervouet C, Becker PD, Chorro L, Carlin LM, Herath S, Papagatsias T, Barbaroux JB, Oh SJ, Benlahrech A, Athanasopoulos T, Dickson G, Patterson S, Kwon SY, Geissmann F, Klavinskis LS
Proceedings of the National Academy of Sciences of the United States of America 2013 Feb 19;110(8):3041-6
Proceedings of the National Academy of Sciences of the United States of America 2013 Feb 19;110(8):3041-6
Human papillomavirus type 8 interferes with a novel C/EBPβ-mediated mechanism of keratinocyte CCL20 chemokine expression and Langerhans cell migration.
Sperling T, Ołdak M, Walch-Rückheim B, Wickenhauser C, Doorbar J, Pfister H, Malejczyk M, Majewski S, Keates AC, Smola S
PLoS pathogens 2012;8(7):e1002833
PLoS pathogens 2012;8(7):e1002833
Human Langerhans cells control Th cells via programmed death-ligand 1 in response to bacterial stimuli and nickel-induced contact allergy.
Hitzler M, Majdic O, Heine G, Worm M, Ebert G, Luch A, Peiser M
PloS one 2012;7(10):e46776
PloS one 2012;7(10):e46776
Aging affects epidermal Langerhans cell development and function and alters their miRNA gene expression profile.
Xu YP, Qi RQ, Chen W, Shi Y, Cui ZZ, Gao XH, Chen HD, Zhou L, Mi QS
Aging 2012 Nov;4(11):742-54
Aging 2012 Nov;4(11):742-54
Age-related changes in expression and function of Toll-like receptors in human skin.
Iram N, Mildner M, Prior M, Petzelbauer P, Fiala C, Hacker S, Schöppl A, Tschachler E, Elbe-Bürger A
Development (Cambridge, England) 2012 Nov;139(22):4210-9
Development (Cambridge, England) 2012 Nov;139(22):4210-9
Langerhans cells require MyD88-dependent signals for Candida albicans response but not for contact hypersensitivity or migration.
Haley K, Igyártó BZ, Ortner D, Bobr A, Kashem S, Schenten D, Kaplan DH
Journal of immunology (Baltimore, Md. : 1950) 2012 May 1;188(9):4334-9
Journal of immunology (Baltimore, Md. : 1950) 2012 May 1;188(9):4334-9
Langerhans cells down-regulate inflammation-driven alveolar bone loss.
Arizon M, Nudel I, Segev H, Mizraji G, Elnekave M, Furmanov K, Eli-Berchoer L, Clausen BE, Shapira L, Wilensky A, Hovav AH
Proceedings of the National Academy of Sciences of the United States of America 2012 May 1;109(18):7043-8
Proceedings of the National Academy of Sciences of the United States of America 2012 May 1;109(18):7043-8
Skin langerin+ dendritic cells transport intradermally injected anti-DEC-205 antibodies but are not essential for subsequent cytotoxic CD8+ T cell responses.
Flacher V, Tripp CH, Haid B, Kissenpfennig A, Malissen B, Stoitzner P, Idoyaga J, Romani N
Journal of immunology (Baltimore, Md. : 1950) 2012 Mar 1;188(5):2146-55
Journal of immunology (Baltimore, Md. : 1950) 2012 Mar 1;188(5):2146-55
CD64 expression distinguishes monocyte-derived and conventional dendritic cells and reveals their distinct role during intramuscular immunization.
Langlet C, Tamoutounour S, Henri S, Luche H, Ardouin L, Grégoire C, Malissen B, Guilliams M
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1751-60
Journal of immunology (Baltimore, Md. : 1950) 2012 Feb 15;188(4):1751-60
Characterization of resident and migratory dendritic cells in human lymph nodes.
Segura E, Valladeau-Guilemond J, Donnadieu MH, Sastre-Garau X, Soumelis V, Amigorena S
The Journal of experimental medicine 2012 Apr 9;209(4):653-60
The Journal of experimental medicine 2012 Apr 9;209(4):653-60
Batf3-dependent CD11b(low/-) peripheral dendritic cells are GM-CSF-independent and are not required for Th cell priming after subcutaneous immunization.
Edelson BT, Bradstreet TR, KC W, Hildner K, Herzog JW, Sim J, Russell JH, Murphy TL, Unanue ER, Murphy KM
PloS one 2011;6(10):e25660
PloS one 2011;6(10):e25660
Protective T cell immunity in mice following protein-TLR7/8 agonist-conjugate immunization requires aggregation, type I IFN, and multiple DC subsets.
Kastenmüller K, Wille-Reece U, Lindsay RW, Trager LR, Darrah PA, Flynn BJ, Becker MR, Udey MC, Clausen BE, Igyarto BZ, Kaplan DH, Kastenmüller W, Germain RN, Seder RA
The Journal of clinical investigation 2011 May;121(5):1782-96
The Journal of clinical investigation 2011 May;121(5):1782-96
Phenotypic localization of distinct DC subsets in mouse Peyer Patch.
Rochereau N, Verrier B, Pin JJ, Genin C, Paul S
Vaccine 2011 May 9;29(20):3655-61
Vaccine 2011 May 9;29(20):3655-61
Calcitonin gene-related peptide is an important regulator of cutaneous immunity: effect on dendritic cell and T cell functions.
Mikami N, Matsushita H, Kato T, Kawasaki R, Sawazaki T, Kishimoto T, Ogitani Y, Watanabe K, Miyagi Y, Sueda K, Fukada S, Yamamoto H, Tsujikawa K
Journal of immunology (Baltimore, Md. : 1950) 2011 Jun 15;186(12):6886-93
Journal of immunology (Baltimore, Md. : 1950) 2011 Jun 15;186(12):6886-93
Characterization of dendritic cells subpopulations in skin and afferent lymph in the swine model.
Marquet F, Bonneau M, Pascale F, Urien C, Kang C, Schwartz-Cornil I, Bertho N
PloS one 2011 Jan 27;6(1):e16320
PloS one 2011 Jan 27;6(1):e16320
Langerin+ dermal dendritic cells are critical for CD8+ T cell activation and IgH γ-1 class switching in response to gene gun vaccines.
Stoecklinger A, Eticha TD, Mesdaghi M, Kissenpfennig A, Malissen B, Thalhamer J, Hammerl P
Journal of immunology (Baltimore, Md. : 1950) 2011 Feb 1;186(3):1377-83
Journal of immunology (Baltimore, Md. : 1950) 2011 Feb 1;186(3):1377-83
The earliest intrathymic precursors of CD8α(+) thymic dendritic cells correspond to myeloid-type double-negative 1c cells.
Luche H, Ardouin L, Teo P, See P, Henri S, Merad M, Ginhoux F, Malissen B
European journal of immunology 2011 Aug;41(8):2165-75
European journal of immunology 2011 Aug;41(8):2165-75
Acute ablation of Langerhans cells enhances skin immune responses.
Bobr A, Olvera-Gomez I, Igyarto BZ, Haley KM, Hogquist KA, Kaplan DH
Journal of immunology (Baltimore, Md. : 1950) 2010 Oct 15;185(8):4724-8
Journal of immunology (Baltimore, Md. : 1950) 2010 Oct 15;185(8):4724-8
Characterization of human DNGR-1+ BDCA3+ leukocytes as putative equivalents of mouse CD8alpha+ dendritic cells.
Poulin LF, Salio M, Griessinger E, Anjos-Afonso F, Craciun L, Chen JL, Keller AM, Joffre O, Zelenay S, Nye E, Le Moine A, Faure F, Donckier V, Sancho D, Cerundolo V, Bonnet D, Reis e Sousa C
The Journal of experimental medicine 2010 Jun 7;207(6):1261-71
The Journal of experimental medicine 2010 Jun 7;207(6):1261-71
CD207+ CD103+ dermal dendritic cells cross-present keratinocyte-derived antigens irrespective of the presence of Langerhans cells.
Henri S, Poulin LF, Tamoutounour S, Ardouin L, Guilliams M, de Bovis B, Devilard E, Viret C, Azukizawa H, Kissenpfennig A, Malissen B
The Journal of experimental medicine 2010 Jan 18;207(1):189-206
The Journal of experimental medicine 2010 Jan 18;207(1):189-206
Functional redundancy of Langerhans cells and Langerin+ dermal dendritic cells in contact hypersensitivity.
Noordegraaf M, Flacher V, Stoitzner P, Clausen BE
The Journal of investigative dermatology 2010 Dec;130(12):2752-9
The Journal of investigative dermatology 2010 Dec;130(12):2752-9
Herpes simplex virus type 2 enhances HIV-1 susceptibility by affecting Langerhans cell function.
de Jong MA, de Witte L, Taylor ME, Geijtenbeek TB
Journal of immunology (Baltimore, Md. : 1950) 2010 Aug 1;185(3):1633-41
Journal of immunology (Baltimore, Md. : 1950) 2010 Aug 1;185(3):1633-41
Langerhans cell (LC) proliferation mediates neonatal development, homeostasis, and inflammation-associated expansion of the epidermal LC network.
Chorro L, Sarde A, Li M, Woollard KJ, Chambon P, Malissen B, Kissenpfennig A, Barbaroux JB, Groves R, Geissmann F
The Journal of experimental medicine 2009 Dec 21;206(13):3089-100
The Journal of experimental medicine 2009 Dec 21;206(13):3089-100
The lymph vessel network in mouse skin visualised with antibodies against the hyaluronan receptor LYVE-1.
Tripp CH, Haid B, Flacher V, Sixt M, Peter H, Farkas J, Gschwentner R, Sorokin L, Romani N, Stoitzner P
Immunobiology 2008;213(9-10):715-28
Immunobiology 2008;213(9-10):715-28
Inefficient presentation of tumor-derived antigen by tumor-infiltrating dendritic cells.
Stoitzner P, Green LK, Jung JY, Price KM, Atarea H, Kivell B, Ronchese F
Cancer immunology, immunotherapy : CII 2008 Nov;57(11):1665-73
Cancer immunology, immunotherapy : CII 2008 Nov;57(11):1665-73
Expression of langerin/CD207 reveals dendritic cell heterogeneity between inbred mouse strains.
Flacher V, Douillard P, Aït-Yahia S, Stoitzner P, Clair-Moninot V, Romani N, Saeland S
Immunology 2008 Mar;123(3):339-47
Immunology 2008 Mar;123(3):339-47
Epidermal and dermal dendritic cells display differential activation and migratory behavior while sharing the ability to stimulate CD4+ T cell proliferation in vivo.
Shklovskaya E, Roediger B, Fazekas de St Groth B
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):418-30
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):418-30
Epidermal and dermal dendritic cells display differential activation and migratory behavior while sharing the ability to stimulate CD4+ T cell proliferation in vivo.
Shklovskaya E, Roediger B, Fazekas de St Groth B
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):418-30
Journal of immunology (Baltimore, Md. : 1950) 2008 Jul 1;181(1):418-30
Langerhans cells in porcine skin.
Nfon CK, Dawson H, Toka FN, Golde WT
Veterinary immunology and immunopathology 2008 Dec 15;126(3-4):236-47
Veterinary immunology and immunopathology 2008 Dec 15;126(3-4):236-47
Langerhans cells and lymph node dendritic cells express the tight junction component claudin-1.
Zimmerli SC, Hauser C
The Journal of investigative dermatology 2007 Oct;127(10):2381-90
The Journal of investigative dermatology 2007 Oct;127(10):2381-90
Autocrine/paracrine TGFbeta1 is required for the development of epidermal Langerhans cells.
Kaplan DH, Li MO, Jenison MC, Shlomchik WD, Flavell RA, Shlomchik MJ
The Journal of experimental medicine 2007 Oct 29;204(11):2545-52
The Journal of experimental medicine 2007 Oct 29;204(11):2545-52
Epidermal langerhans cells are dispensable for humoral and cell-mediated immunity elicited by gene gun immunization.
Stoecklinger A, Grieshuber I, Scheiblhofer S, Weiss R, Ritter U, Kissenpfennig A, Malissen B, Romani N, Koch F, Ferreira F, Thalhamer J, Hammerl P
Journal of immunology (Baltimore, Md. : 1950) 2007 Jul 15;179(2):886-93
Journal of immunology (Baltimore, Md. : 1950) 2007 Jul 15;179(2):886-93
Epidermal langerhans cells are dispensable for humoral and cell-mediated immunity elicited by gene gun immunization.
Stoecklinger A, Grieshuber I, Scheiblhofer S, Weiss R, Ritter U, Kissenpfennig A, Malissen B, Romani N, Koch F, Ferreira F, Thalhamer J, Hammerl P
Journal of immunology (Baltimore, Md. : 1950) 2007 Jul 15;179(2):886-93
Journal of immunology (Baltimore, Md. : 1950) 2007 Jul 15;179(2):886-93
Identification of a novel population of Langerin+ dendritic cells.
Bursch LS, Wang L, Igyarto B, Kissenpfennig A, Malissen B, Kaplan DH, Hogquist KA
The Journal of experimental medicine 2007 Dec 24;204(13):3147-56
The Journal of experimental medicine 2007 Dec 24;204(13):3147-56
The dermis contains langerin+ dendritic cells that develop and function independently of epidermal Langerhans cells.
Poulin LF, Henri S, de Bovis B, Devilard E, Kissenpfennig A, Malissen B
The Journal of experimental medicine 2007 Dec 24;204(13):3119-31
The Journal of experimental medicine 2007 Dec 24;204(13):3119-31
Peroxisome proliferator-activated receptor-alpha activation inhibits Langerhans cell function.
Dubrac S, Stoitzner P, Pirkebner D, Elentner A, Schoonjans K, Auwerx J, Saeland S, Hengster P, Fritsch P, Romani N, Schmuth M
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 1;178(7):4362-72
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 1;178(7):4362-72
Peroxisome proliferator-activated receptor-alpha activation inhibits Langerhans cell function.
Dubrac S, Stoitzner P, Pirkebner D, Elentner A, Schoonjans K, Auwerx J, Saeland S, Hengster P, Fritsch P, Romani N, Schmuth M
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 1;178(7):4362-72
Journal of immunology (Baltimore, Md. : 1950) 2007 Apr 1;178(7):4362-72
Neutrophils rapidly migrate via lymphatics after Mycobacterium bovis BCG intradermal vaccination and shuttle live bacilli to the draining lymph nodes.
Abadie V, Badell E, Douillard P, Ensergueix D, Leenen PJ, Tanguy M, Fiette L, Saeland S, Gicquel B, Winter N
Blood 2005 Sep 1;106(5):1843-50
Blood 2005 Sep 1;106(5):1843-50
Mouse lymphoid tissue contains distinct subsets of langerin/CD207 dendritic cells, only one of which represents epidermal-derived Langerhans cells.
Douillard P, Stoitzner P, Tripp CH, Clair-Moninot V, Aït-Yahia S, McLellan AD, Eggert A, Romani N, Saeland S
The Journal of investigative dermatology 2005 Nov;125(5):983-94
The Journal of investigative dermatology 2005 Nov;125(5):983-94
Disruption of the langerin/CD207 gene abolishes Birbeck granules without a marked loss of Langerhans cell function.
Kissenpfennig A, Aït-Yahia S, Clair-Moninot V, Stössel H, Badell E, Bordat Y, Pooley JL, Lang T, Prina E, Coste I, Gresser O, Renno T, Winter N, Milon G, Shortman K, Romani N, Lebecque S, Malissen B, Saeland S, Douillard P
Molecular and cellular biology 2005 Jan;25(1):88-99
Molecular and cellular biology 2005 Jan;25(1):88-99
Epidermal langerhans cell-deficient mice develop enhanced contact hypersensitivity.
Kaplan DH, Jenison MC, Saeland S, Shlomchik WD, Shlomchik MJ
Immunity 2005 Dec;23(6):611-20
Immunity 2005 Dec;23(6):611-20
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Liénard D, Gugerli O, Ferradini L, Robert C, Avril MF, Zitvogel L, Angevin E
Cancer research 2004 Mar 15;64(6):2192-8
Cancer research 2004 Mar 15;64(6):2192-8
Selective accumulation of mature DC-Lamp+ dendritic cells in tumor sites is associated with efficient T-cell-mediated antitumor response and control of metastatic dissemination in melanoma.
Movassagh M, Spatz A, Davoust J, Lebecque S, Romero P, Pittet M, Rimoldi D, Liénard D, Gugerli O, Ferradini L, Robert C, Avril MF, Zitvogel L, Angevin E
Cancer research 2004 Mar 15;64(6):2192-8
Cancer research 2004 Mar 15;64(6):2192-8
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Valladeau J, Clair-Moninot V, Dezutter-Dambuyant C, Pin JJ, Kissenpfennig A, Mattéi MG, Ait-Yahia S, Bates EE, Malissen B, Koch F, Fossiez F, Romani N, Lebecque S, Saeland S
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Identification of mouse langerin/CD207 in Langerhans cells and some dendritic cells of lymphoid tissues.
Valladeau J, Clair-Moninot V, Dezutter-Dambuyant C, Pin JJ, Kissenpfennig A, Mattéi MG, Ait-Yahia S, Bates EE, Malissen B, Koch F, Fossiez F, Romani N, Lebecque S, Saeland S
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
Journal of immunology (Baltimore, Md. : 1950) 2002 Jan 15;168(2):782-92
No comments: Submit comment
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: Langerin/CD207 Antibody (929F3.01) [DDX0362P-100] - Analysis using the HRP conjugate of DDX0362P-100. Staining of human skin frozen section.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Frozen: Langerin/CD207 Antibody (929F3.01) [DDX0362P-100] - IHC staining of human skin cryosections with 929F3-HRP
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry: Langerin/CD207 Antibody (929F3.01) [DDX0362P-100] - Epidermal LC are dispensable for betaGal-specific immunity but down-regulate OVA-specific T cell functions. LangDTR or B6 WT mice were injected once with 1ug DT. Epidermal sheets were stained for langerin expression 3 wks later. Image collected and cropped by CiteAb from the following publication (http://dx.plos.org/10.1371/journal.pone.0128722), licensed under a CC-BY licence.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Flow Cytometry: Langerin/CD207 Antibody (929F3.01) [DDX0362P-100] - Cells derived from culture of porcine skin stained permeabilized (D) or not (C) with 929F3
