ERP27

This gene encodes a noncatalytic member of the protein disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins. The canonical protein has an N-terminal signal sequence, two thioredoxin (TRX)-like domains and a C-terminal ER-retention sequence. Alternative splicing results in multiple transcript variants encoding distinct isoforms; some of which lack domains present in the canonical protein. [provided by RefSeq, Dec 2016]

Description

Endoplasmic reticulum protein 27

Tissue specificity

Tissue enriched (pancreas)

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Kim et al 2014)

Chromosome

12 (14914039 - 14938537)

Ensembl ID

ENSG00000139055  (ver. 103.38)

Orthologs

Mouse Erp27: ENSMUSG00000030219

UniProt

Q96DN0

neXtProt

NX_Q96DN0

Human splice variants
Mouse splice variants

Protein structure