ARHGAP6

This gene encodes a member of the rhoGAP family of proteins which play a role in the regulation of actin polymerization at the plasma membrane during several cellular processes. This protein is thought to have two independent functions, one as a GTPase-activating protein with specificity for RhoA, and another as a cytoskeletal protein that promotes actin remodeling. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Description

Rho GTPase activating protein 6

Protein family

Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

X:p22.2 (11117651 - 11665920)

Ensembl ID

ENSG00000047648  (ver. 99.38)

Orthologs

Mouse Arhgap6: ENSMUSG00000031355

UniProt

O43182

neXtProt

NX_O43182

Human splice variants
Mouse splice variants