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Western blotAntibody data
- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Western blot [1]
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- Product number
- PAB12503 - Provider product page
- Provider
- Abnova Corporation
- Proper citation
- Abnova Corporation Cat#PAB12503, RRID:AB_10547996
- Product name
- ABCG1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- Rabbit polyclonal antibody raised against synthetic peptide of ABCG1.
- Storage
- Store at 4°C. Do not freeze.
Submitted references LXR-induced reverse cholesterol transport in human airway smooth muscle is mediated exclusively by ABCA1.
ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo.
The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein.
Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways.
Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow.
Delvecchio CJ, Bilan P, Nair P, Capone JP
American journal of physiology. Lung cellular and molecular physiology 2008 Nov;295(5):L949-57
American journal of physiology. Lung cellular and molecular physiology 2008 Nov;295(5):L949-57
ABCG1 influences the brain cholesterol biosynthetic pathway but does not affect amyloid precursor protein or apolipoprotein E metabolism in vivo.
Burgess BL, Parkinson PF, Racke MM, Hirsch-Reinshagen V, Fan J, Wong C, Stukas S, Theroux L, Chan JY, Donkin J, Wilkinson A, Balik D, Christie B, Poirier J, Lütjohann D, Demattos RB, Wellington CL
Journal of lipid research 2008 Jun;49(6):1254-67
Journal of lipid research 2008 Jun;49(6):1254-67
The cholesterol transporter ABCG1 modulates the subcellular distribution and proteolytic processing of beta-amyloid precursor protein.
Tansley GH, Burgess BL, Bryan MT, Su Y, Hirsch-Reinshagen V, Pearce J, Chan JY, Wilkinson A, Evans J, Naus KE, McIsaac S, Bromley K, Song W, Yang HC, Wang N, DeMattos RB, Wellington CL
Journal of lipid research 2007 May;48(5):1022-34
Journal of lipid research 2007 May;48(5):1022-34
Different cellular traffic of LDL-cholesterol and acetylated LDL-cholesterol leads to distinct reverse cholesterol transport pathways.
Wang MD, Kiss RS, Franklin V, McBride HM, Whitman SC, Marcel YL
Journal of lipid research 2007 Mar;48(3):633-45
Journal of lipid research 2007 Mar;48(3):633-45
Decreased atherosclerosis in low-density lipoprotein receptor knockout mice transplanted with Abcg1-/- bone marrow.
Ranalletta M, Wang N, Han S, Yvan-Charvet L, Welch C, Tall AR
Arteriosclerosis, thrombosis, and vascular biology 2006 Oct;26(10):2308-15
Arteriosclerosis, thrombosis, and vascular biology 2006 Oct;26(10):2308-15
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Supportive validation
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- Abnova Corporation (provider)
- Main image
- Experimental details
- Detection of ABCG1 in mouse peritoneal macrophages (40 ug) using ABCG1 polyclonal antibody (Cat # PAB12503). Lane 1 : positive ABCG1 control, lane 2 : 10 uM 22- (R) -hydrocholesterol treated macrophages, Lane 3 : 100 nM T0901713 (LXRa ligand) treated macrophages, and Lane 4 : 500 nM T091713 (LXRa ligand) treated macrophages.
