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SUCLA2
Succinate-CoA ligase ADP-forming subunit betaLINC00444
Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit. The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle. SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA. Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome. A pseudogene of this gene has been found on chromosome 6. [provided by RefSeq, Jul 2008]
Top validated antibodies |
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| Proteintech Group |  12627-1-AP |
13 references | Polyclonal |
WB
EL
ICC
IP
IHC
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| Invitrogen Antibodies | 12627-1-AP |
Polyclonal |
WB
ICC
IP
IHC
OA
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| GeneTex | GTX109728 |
3 references | Polyclonal |
WB
ICC
IHC
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| Atlas Antibodies | HPA039536 |
Polyclonal |
WB
ICC
IHC
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| LSBio | LS-C186095 |
Polyclonal |
WB
ICC
IHC
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