Antibody data
- Antibody Data
- Antigen structure
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- Product number
- CABT-B1889 - Provider product page
- Provider
- Creative Diagnostics
- Product name
- Anti-DMRT1 polyclonal antibody
- Antibody type
- Polyclonal
- Description
- DMRT1 (Doublesex and mab-3 related transcription factor 1), a 39.4 kDa protein, acts as a transcription factor and plays a key role in male sex determination and differentiation by controlling testis development and male germ cell proliferation. DMRT1 maintains SOX9 and suppresses FOXL2 expression in postnatal Sertoli cells, which prevents feminization of males. DMRT1 mutants can become feminized during the first postnatal month. Defects in DMRT1 have been linked to testicular germ cell tumors.
- Reactivity
- Human
- Host
- Rabbit
- Conjugate
- Unconjugated
- Isotype
- IgG
- Vial size
- 100 _L
- Concentration
- Please refer to lot specific datasheet.
- Storage
- Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.
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