13681-1-AP

antibody from Proteintech Group

Targeting: TFF2 SML1

Western blot (Supportive data in Antibodypedia)

ELISA (Data presented on provider website)

Immunoprecipitation (Data presented on provider website)

Immunohistochemistry (Supportive data in Antibodypedia)

Antibody Data

Product number

13681-1-AP

Provider

Proteintech Group

Proper citation

Proteintech Cat#13681-1-AP, RRID:AB_10598321

Product name

TFF2 antibody

Antibody type

Polyclonal

Description

TFF2 antibody (Cat. #13681-1-AP) is a rabbit polyclonal antibody that shows reactivity with human, mouse and has been validated for the following applications: IHC, IP, WB,ELISA.

Reactivity

Human, Mouse

Host

Rabbit

Conjugate

Unconjugated

Isotype

IgG

Vial size

20ul, 150ul

References

Submitted references

Programmed Death Ligand 1-Expressing Classical Dendritic Cells MitigateHelicobacter-Induced Gastritis.

Go DM, Lee SH, Lee SH, Woo SH, Kim K, Kim K, Park KS, Park JH, Ha SJ, Kim WH, Choi JH, Kim DY
Cellular and molecular gastroenterology and hepatology 2021;12(2):715-739

---

Epstein-Barr virus associated gastric dysplasia: a new rare entity?

Angerilli V, Galuppini F, Pennelli G, Fanelli GN, d'Amore ESG, Michelotto M, Pilati P, Spolverato G, Pucciarelli S, Scarpa M, Farinati F, Savarino E, Realdon S, Lonardi S, Bergamo F, Loupakis F, Dei Tos AP, Vanoli A, Fassan M
Virchows Archiv : an international journal of pathology 2021 Sep 19;

---

Vaginal mucus in mice: developmental and gene expression features of epithelial mucous cells during pregnancy†.

Sugiyama M, Machida N, Yasunaga A, Terai N, Fukasawa H, Ono HK, Kobayashi R, Nishiyama K, Hashimoto O, Kurusu S, Yoshioka K
Biology of reproduction 2021 Nov 15;105(5):1272-1282

---

mTOR signaling regulates gastric epithelial progenitor homeostasis and gastric tumorigenesis via MEK1-ERKs and BMP-Smad1 pathways.

Li K, Wu H, Wang A, Charron J, Mishina Y, Habib SL, Liu H, Li B
Cell reports 2021 May 4;35(5):109069

---

Differential chromatin binding of the lung lineage transcription factor NKX2-1 resolves opposing murine alveolar cell fates in vivo.

Little DR, Lynch AM, Yan Y, Akiyama H, Kimura S, Chen J
Nature communications 2021 May 4;12(1):2509

---

Dissecting transcriptional heterogeneity in primary gastric adenocarcinoma by single cell RNA sequencing.

Zhang M, Hu S, Min M, Ni Y, Lu Z, Sun X, Wu J, Liu B, Ying X, Liu Y
Gut 2021 Mar;70(3):464-475

---

Pyloric, pseudopyloric, and spasmolytic polypeptide-expressing metaplasias in autoimmune gastritis: a case series of 22 Japanese patients.

Wada Y, Nakajima S, Kushima R, Takemura S, Mori N, Hasegawa H, Nakayama T, Mukaisho KI, Yoshida A, Umano S, Yamamoto K, Sugihara H, Murakami K
Virchows Archiv : an international journal of pathology 2021 Jul;479(1):169-178

---

Histological assessment of gastric pseudopyloric metaplasia: Intra- and inter-observer consistency.

Rugge M, Sacchi D, Genta RM, Zanco F, Guzzinati S, Pizzi M, Fassan M, Di Sabatino A, El-Serag H
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver 2021 Jan;53(1):61-65

---

A tumour-resident Lgr5⁺ stem-cell-like pool drives the establishment and progression of advanced gastric cancers.

Fatehullah A, Terakado Y, Sagiraju S, Tan TL, Sheng T, Tan SH, Murakami K, Swathi Y, Ang N, Rajarethinam R, Ming T, Tan P, Lee B, Barker N
Nature cell biology 2021 Dec;23(12):1299-1313

---

Induction of Gastric Cancer by Successive Oncogenic Activation in the Corpus.

Douchi D, Yamamura A, Matsuo J, Melissa Lim YH, Nuttonmanit N, Shimura M, Suda K, Chen S, Pang S, Kohu K, Abe T, Shioi G, Kim G, Shabbir A, Srivastava S, Unno M, Bok-Yan So J, Teh M, Yeoh KG, Huey Chuang LS, Ito Y
Gastroenterology 2021 Dec;161(6):1907-1923.e26

---

Trefoil factor family 2 inhibits cholangiocarcinogenesis by regulating the PTEN pathway in mice.

Hasebe K, Yamaguchi J, Kokuryo T, Yokoyama Y, Ochiai Y, Nagino M, Ebata T
Carcinogenesis 2021 Dec 31;42(12):1496-1505

---

Mast1 mediates radiation-induced gastric injury via the P38 MAPK pathway.

Ding W, Lu Y, Zhou A, Chen Y, Wang Z, Wang L, Tian Y
Experimental cell research 2021 Dec 15;409(2):112913

---

Histological changes associated with pyloric and pseudopyloric metaplasia after Helicobacter pylori eradication.

Wada Y, Kushima R, Kodama M, Fukuda M, Fukuda K, Okamoto K, Ogawa R, Mizukami K, Okimoto T, Murakami K
Virchows Archiv : an international journal of pathology 2020 Oct;477(4):489-496

---

Evidence for heightened genetic instability in precancerous spasmolytic polypeptide expressing gastric glands.

Chen J, Zhu C, Wang C, Hu C, Czajkowsky DM, Guo Y, Liu B, Shao Z
Journal of medical genetics 2020 Jun;57(6):385-388

---

Gastric Corpus Mucosal Hyperplasia and Neuroendocrine Cell Hyperplasia, but not Spasmolytic Polypeptide-Expressing Metaplasia, Is Prevented by a Gastrin Receptor Antagonist in H⁺/K⁺ATPase Beta Subunit Knockout Mice.

Aasarød KM, Waldum HL, Stunes AK, Sandvik AK, Flatberg A, Mjønes P, Syversen U, Bakke I, Fossmark R
International journal of molecular sciences 2020 Jan 31;21(3)

---

Deoxycholic acid-stimulated macrophage-derived exosomes promote spasmolytic polypeptide-expressing metaplasia in the stomach.

Xu X, Cheng J, Luo S, Gong X, Huang D, Xu J, Qian Y, Wan X, Zhou H
Biochemical and biophysical research communications 2020 Apr 9;524(3):649-655

---

Early administration of dapagliflozin preserves pancreatic β-cell mass through a legacy effect in a mouse model of type 2 diabetes.

Kanno A, Asahara SI, Kawamura M, Furubayashi A, Tsuchiya S, Suzuki E, Takai T, Koyanagi-Kimura M, Matsuda T, Okada Y, Ogawa W, Kido Y
Journal of diabetes investigation 2019 May;10(3):577-590

---

Trefoil factor(s) and CA19.9: A promising panel for early detection of pancreatic cancer.

Jahan R, Ganguly K, Smith LM, Atri P, Carmicheal J, Sheinin Y, Rachagani S, Natarajan G, Brand RE, Macha MA, Grandgenett PM, Kaur S, Batra SK
EBioMedicine 2019 Apr;42:375-385

---

Activation of Signal Transduction and Activator of Transcription 3 Signaling Contributes to Helicobacter-Associated Gastric Epithelial Proliferation and Inflammation.

Ishii Y, Shibata W, Sugimori M, Kaneta Y, Kanno M, Sato T, Sue S, Kameta E, Kaneko H, Irie K, Sasaki T, Kondo M, Maeda S
Gastroenterology research and practice 2018;2018:9050715

---

Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity.

Tata PR, Chow RD, Saladi SV, Tata A, Konkimalla A, Bara A, Montoro D, Hariri LP, Shih AR, Mino-Kenudson M, Mou H, Kimura S, Ellisen LW, Rajagopal J
Developmental cell 2018 Mar 26;44(6):679-693.e5

---

Nicotine Induces Progressive Properties of Lung Adenocarcinoma A549 Cells by Inhibiting Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Expression and Plasma Membrane Localization.

Li H, Ma N, Wang J, Wang Y, Yuan C, Wu J, Luo M, Yang J, Chen J, Shi J, Liu X
Technology in cancer research & treatment 2018 Jan 1;17:1533033818809984

---

A revised airway epithelial hierarchy includes CFTR-expressing ionocytes.

Montoro DT, Haber AL, Biton M, Vinarsky V, Lin B, Birket SE, Yuan F, Chen S, Leung HM, Villoria J, Rogel N, Burgin G, Tsankov AM, Waghray A, Slyper M, Waldman J, Nguyen L, Dionne D, Rozenblatt-Rosen O, Tata PR, Mou H, Shivaraju M, Bihler H, Mense M, Tearney GJ, Rowe SM, Engelhardt JF, Regev A, Rajagopal J
Nature 2018 Aug;560(7718):319-324

---

Depletion of club cells attenuates bleomycin-induced lung injury and fibrosis in mice.

Yokoyama T, Yanagihara T, Suzuki K, Hamada N, Tsubouchi K, Ogata-Suetsugu S, Mikumo H, Ikeda-Harada C, Maeyama T, Kuwano K, Nakanishi Y
Journal of inflammation (London, England) 2017;14:20

---

The cytoprotective protein clusterin is overexpressed in hypergastrinemic rodent models of oxyntic preneoplasia and promotes gastric cancer cell survival.

Vange P, Bruland T, Doseth B, Fossmark R, Sousa MML, Beisvag V, Sørdal Ø, Qvigstad G, Waldum HL, Sandvik AK, Bakke I
PloS one 2017;12(9):e0184514

---

Clinical significance of spasmolytic polypeptide-expressing metaplasia and intestinal metaplasia in Epstein-Barr virus-associated and Epstein-Barr virus-negative gastric cancer.

Zhang Y, Chen JN, Dong M, Zhang ZG, Zhang YW, Wu JY, Du H, Li HG, Huang Y, Shao CK
Human pathology 2017 May;63:128-138

---

Lgr5-expressing chief cells drive epithelial regeneration and cancer in the oxyntic stomach.

Leushacke M, Tan SH, Wong A, Swathi Y, Hajamohideen A, Tan LT, Goh J, Wong E, Denil SLIJ, Murakami K, Barker N
Nature cell biology 2017 Jul;19(7):774-786

---

Goblet Cell Ratio in Combination with Differentiation and Stem Cell Markers in Barrett Esophagus Allow Distinction of Patients with and without Esophageal Adenocarcinoma.

Schellnegger R, Quante A, Rospleszcz S, Schernhammer M, Höhl B, Tobiasch M, Pastula A, Brandtner A, Abrams JA, Strauch K, Schmid RM, Vieth M, Wang TC, Quante M
Cancer prevention research (Philadelphia, Pa.) 2017 Jan;10(1):55-66

---

Ink4a/Arf-Dependent Loss of Parietal Cells Induced by Oxidative Stress Promotes CD44-Dependent Gastric Tumorigenesis.

Seishima R, Wada T, Tsuchihashi K, Okazaki S, Yoshikawa M, Oshima H, Oshima M, Sato T, Hasegawa H, Kitagawa Y, Goldenring JR, Saya H, Nagano O
Cancer prevention research (Philadelphia, Pa.) 2015 Jun;8(6):492-501

---

Heterogeneous Nuclear Ribonucleoprotein A1 Improves the Intestinal Injury by Regulating Apoptosis Through Trefoil Factor 2 in Mice with Anti-CD3-induced Enteritis.

Ando K, Fujiya M, Konishi H, Ueno N, Inaba Y, Moriichi K, Ikuta K, Tanabe H, Ohtake T, Kohgo Y
Inflammatory bowel diseases 2015 Jul;21(7):1541-52

---

Pancreatic duct glands (PDGs) are a progenitor compartment responsible for pancreatic ductal epithelial repair.

Yamaguchi J, Liss AS, Sontheimer A, Mino-Kenudson M, Castillo CF, Warshaw AL, Thayer SP
Stem cell research 2015 Jul;15(1):190-202

---

RNA sequencing of sessile serrated colon polyps identifies differentially expressed genes and immunohistochemical markers.

Delker DA, McGettigan BM, Kanth P, Pop S, Neklason DW, Bronner MP, Burt RW, Hagedorn CH
PloS one 2014;9(2):e88367

---

Promoter hypermethylation and downregulation of trefoil factor 2 in human gastric cancer.

Jiang P, Yu G, Zhang Y, Xiang Y, Zhu Z, Feng W, Lee W, Zhang Y
Oncology letters 2014 May;7(5):1525-1531

Western blot

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

human stomach tissue were subjected to SDS PAGE followed by western blot with 13681-1-AP(TFF2 antibody) at dilution of 1:100

Sample type

tissue

Immunohistochemistry

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

Immunohistochemical of paraffin-embedded human stomach cancer using 13681-1-AP(TFF2 antibody) at dilution of 1:50 (under 10x lens)

Sample type

tissue

Supportive validation

Submitted by

Proteintech Group (provider)

Main image

Experimental details

The TFF2 antibody from Proteintech is a rabbit polyclonal antibody to a recombinant protein of human TFF2. This antibody recognizes human,mouse,rat antigen. The TFF2 antibody has been validated for the following applications: ELISA, IHC, WB analysis.

Appendix

13681-1-AP.pdf

Show more