ALG5

This gene encodes a member of the glycosyltransferase 2 family. The encoded protein participates in glucosylation of the oligomannose core in N-linked glycosylation of proteins. The addition of glucose residues to the oligomannose core is necessary to ensure substrate recognition, and therefore, effectual transfer of the oligomannose core to the nascent glycoproteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008]

Description

ALG5 dolichyl-phosphate beta-glucosyltransferase

Tissue specificity

Low tissue specificity

Subcell location

Cytosol

Predicted location

Intracellular, Membrane

Protein family

Enzymes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Metabolic proteins
Predicted intracellular proteins
Predicted membrane proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

13 (36949738 - 37000763)

Ensembl ID

ENSG00000120697  (ver. 103.38)

Orthologs

Mouse Alg5: ENSMUSG00000036632

UniProt

Q9Y673

neXtProt

NX_Q9Y673

Human splice variants
Mouse splice variants

Protein structure