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Protein structure
SETDB2
SET domain bifurcated histone lysine methyltransferase 2C13orf4, CLLD8, CLLL8, KMT1F
This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Top validated antibodies |
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| Novus Biologicals |  NB100-1137 |
2 references | Polyclonal |
WB
EL
ICC
IP
ChIP
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| Invitrogen Antibodies | PA5-30848 |
1 references | Polyclonal |
WB
ICC
OA
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| antibodies-online | ABIN393380 |
5 references | Monoclonal |
WB
EL
|
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| GeneTex | GTX116932 |
Polyclonal |
WB
ICC
IP
|
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| Affinity Biosciences | DF2566 |
Polyclonal |
WB
EL
IHC
|
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