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- Product number
- ABIN395874 - Provider product page
- Provider
- antibodies-online
- Product name
- anti-Adaptor-Related Protein Complex 1, sigma 2 Subunit (AP1S2) (AA 1-158) antibody
- Antibody type
- Monoclonal
- Description
- This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
- Reactivity
- Human
- Host
- Mouse
- Epitope
- AA 1-158
- Isotype
- IgG
- Antibody clone number
- 3B9-G5
- Vial size
- 100 μg
- Storage
- Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Submitted references Clinical, cellular, and neuropathological consequences of AP1S2 mutations: further delineation of a recognizable X-linked mental retardation syndrome.
Mutations in the AP1S2 gene encoding the sigma 2 subunit of the adaptor protein 1 complex are associated with syndromic X-linked mental retardation with hydrocephalus and calcifications in basal ganglia.
HIV-1 Nef stabilizes AP-1 on membranes without inducing ARF1-independent de novo attachment.
Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.
Leucine-specific, functional interactions between human immunodeficiency virus type 1 Nef and adaptor protein complexes.
Borck G, Mollà-Herman A, Boddaert N, Encha-Razavi F, Philippe A, Robel L, Desguerre I, Brunelle F, Benmerah A, Munnich A, Colleaux L
Human mutation 2008 Jul;29(7):966-74
Human mutation 2008 Jul;29(7):966-74
Mutations in the AP1S2 gene encoding the sigma 2 subunit of the adaptor protein 1 complex are associated with syndromic X-linked mental retardation with hydrocephalus and calcifications in basal ganglia.
Saillour Y, Zanni G, Des Portes V, Heron D, Guibaud L, Iba-Zizen MT, Pedespan JL, Poirier K, Castelnau L, Julien C, Franconnet C, Bonthron D, Porteous ME, Chelly J, Bienvenu T
Journal of medical genetics 2007 Nov;44(11):739-44
Journal of medical genetics 2007 Nov;44(11):739-44
HIV-1 Nef stabilizes AP-1 on membranes without inducing ARF1-independent de novo attachment.
Coleman SH, Hitchin D, Noviello CM, Guatelli JC
Virology 2006 Feb 5;345(1):148-55
Virology 2006 Feb 5;345(1):148-55
Mutations in the gene encoding the Sigma 2 subunit of the adaptor protein 1 complex, AP1S2, cause X-linked mental retardation.
Tarpey PS, Stevens C, Teague J, Edkins S, O'Meara S, Avis T, Barthorpe S, Buck G, Butler A, Cole J, Dicks E, Gray K, Halliday K, Harrison R, Hills K, Hinton J, Jones D, Menzies A, Mironenko T, Perry J, Raine K, Richardson D, Shepherd R, Small A, Tofts C, Varian J, West S, Widaa S, Yates A, Catford R, Butler J, Mallya U, Moon J, Luo Y, Dorkins H, Thompson D, Easton DF, Wooster R, Bobrow M, Carpenter N, Simensen RJ, Schwartz CE, Stevenson RE, Turner G, Partington M, Gecz J, Stratton MR, Futreal PA, Raymond FL
American journal of human genetics 2006 Dec;79(6):1119-24
American journal of human genetics 2006 Dec;79(6):1119-24
Leucine-specific, functional interactions between human immunodeficiency virus type 1 Nef and adaptor protein complexes.
Coleman SH, Van Damme N, Day JR, Noviello CM, Hitchin D, Madrid R, Benichou S, Guatelli JC
Journal of virology 2005 Feb;79(4):2066-78
Journal of virology 2005 Feb;79(4):2066-78
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