BS8585

antibody from Bioworld Technology, Inc
Targeting: HLA-DMA D6S222E, RING6
Provider product page for BS8585
Western blot
Immunohistochemistry

Antibody data

Product number
BS8585 - Provider product page
Provider
Bioworld Technology, Inc
Product name
HLA DMA polyclonal antibody
Antibody type
Polyclonal
Antigen
HLA class II histocompatibility antigen, DM alpha chain; MHC class II antigen DMA; Really interesting new gene 6 protein; HLA-DMA; DMA, RING6
Description
HLA-DMA belongs to the HLA class II alpha chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DMA) and a beta chain (DMB), both anchored in the membrane. It is located in intracellular vesicles. DM plays a central role in the peptide loading of MHC class II molecules by helping to release the CLIP molecule from the peptide binding site. Class II molecules are expressed in antigen presenting cells (APC: B lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa and its gene contains 5 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and the cytoplasmic tail.
Reactivity
Human, Mouse
Host
Rabbit
Isotype
IgG
Vial size
100ul
Concentration
1 mg/ml
Storage
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
HLA-DMA protein structure - BS8585 shown in red.