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- Western blot [3]
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- Product number
- NBP1-85209 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NBP1-85209, RRID:AB_11031284
- Product name
- Rabbit Polyclonal DIS3 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Specificity of human DIS3 antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 0.1 ml
- Storage
- Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Submitted references Multiple myeloma-associated hDIS3 mutations cause perturbations in cellular RNA metabolism and suggest hDIS3 PIN domain as a potential drug target.
Tomecki R, Drazkowska K, Kucinski I, Stodus K, Szczesny RJ, Gruchota J, Owczarek EP, Kalisiak K, Dziembowski A
Nucleic acids research 2014 Jan;42(2):1270-90
Nucleic acids research 2014 Jan;42(2):1270-90
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DIS3 Antibody [NBP1-85209] - Analysis in human cell line U-87 MG.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DIS3 Antibody [NBP1-85209] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: DIS3 Antibody [NBP1-85209] - Analysis in U-87MG ATCC cells transfected with control siRNA, target specific siRNA probe #1 and #2,. Remaining relative intensity is presented. Loading control: Anti-GAPDH.
Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Immunohistochemistry-Paraffin: DIS3 Antibody [NBP1-85209] - Staining of human colon shows moderate nuclear positivity in glandular cells.
