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CHIT1
Chitinase 1CHI3, CHIT
Chitotriosidase is secreted by activated human macrophages and is markedly elevated in plasma of Gaucher disease patients. The expression of chitotriosidase occurs only at a late stage of differentiation of monocytes to activated macrophages in culture. Human macrophages can synthesize a functional chitotriosidase, a highly conserved enzyme with a strongly regulated expression. This enzyme may play a role in the degradation of chitin-containing pathogens. Several alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jan 2012]
Top validated antibodies |
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| Novus Biologicals |  NBP1-84490 |
1 references | Polyclonal |
WB
IHC
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| antibodies-online | ABIN4297944 |
Polyclonal |
WB
ICC
IHC
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| R&D Systems | AF3559 |
2 references | Polyclonal |
WB
IP
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| Proteintech Group | 21432-1-AP |
Polyclonal |
WB
EL
IHC
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| Biorbyt | orb1279122 |
Polyclonal |
WB
EL
IHC
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