GTX103289

Zhang ML, Zheng B, Tong F, Yang Z, Wang ZB, Yang BM, Sun Y, Zhang XH, Zhao YL, Wen JK
Biochimica et biophysica acta. Molecular basis of disease 2017 Nov;1863(11):2821-2834

KLF5 promotes cervical cancer proliferation, migration and invasion in a manner partly dependent on TNFRSF11a expression.

Ma D, Chang LY, Zhao S, Zhao JJ, Xiong YJ, Cao FY, Yuan L, Zhang Q, Wang XY, Geng ML, Zheng HY, Li O
Scientific reports 2017 Nov 16;7(1):15683

Krüppel Like Factors Family Expression in Cervical Cancer Cells.

Marrero-Rodríguez D, la Cruz HA, Taniguchi-Ponciano K, Gomez-Virgilio L, Huerta-Padilla V, Ponce-Navarrete G, Andonegui-Elguera S, Jimenez-Vega F, Romero-Morelos P, Rodriguez-Esquivel M, Meraz-Rios M, Figueroa-Corona MDP, Monroy A, Pérez-González O, Salcedo M
Archives of medical research 2017 May;48(4):314-322

1, 25(OH)₂D₃-induced interaction of vitamin D receptor with p50 subunit of NF-κB suppresses the interaction between KLF5 and p50, contributing to inhibition of LPS-induced macrophage proliferation.

Ma D, Zhang RN, Wen Y, Yin WN, Bai D, Zheng GY, Li JS, Zheng B, Wen JK
Biochemical and biophysical research communications 2017 Jan 8;482(2):366-374

Tongxinluo inhibits neointimal formation by regulating the expression and post-translational modification of KLF5 in macrophages.

Jiang W, Zheng B, Zhang XH, Yue LY, Liu C, Ma D, Yang Z, Wen JK
American journal of translational research 2016;8(11):4778-4790

Roles of Klf5 Acetylation in the Self-Renewal and the Differentiation of Mouse Embryonic Stem Cells.

Zhao T, Liu C, Chen L
PloS one 2015;10(9):e0138168

KLF5 regulates infection- and inflammation-induced pro-labour mediators in human myometrium.

Lappas M
Reproduction (Cambridge, England) 2015 May;149(5):413-24

Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism.

Hu Z, Zhu D, Wang W, Li W, Jia W, Zeng X, Ding W, Yu L, Wang X, Wang L, Shen H, Zhang C, Liu H, Liu X, Zhao Y, Fang X, Li S, Chen W, Tang T, Fu A, Wang Z, Chen G, Gao Q, Li S, Xi L, Wang C, Liao S, Ma X, Wu P, Li K, Wang S, Zhou J, Wang J, Xu X, Wang H, Ma D
Nature genetics 2015 Feb;47(2):158-63

Krüppel-like factor 5 mediates proinflammatory cytokine expression in lipopolysaccharide-induced acute lung injury through upregulation of nuclear factor-κB phosphorylation in vitro and in vivo.

Chen HL, Chong IW, Lee YC, Tsai JR, Yuan SS, Wang HM, Liu WL, Liu PL
Mediators of inflammation 2014;2014:281984

Krüppel-like factor 5 as potential molecular marker in cervical cancer and the KLF family profile expression.

Marrero-Rodríguez D, Taniguchi-Ponciano K, Jimenez-Vega F, Romero-Morelos P, Mendoza-Rodríguez M, Mantilla A, Rodriguez-Esquivel M, Hernandez D, Hernandez A, Gomez-Gutierrez G, Muñoz-Hernandez N, la Cruz HA, Vargas-Requena C, Díaz-Hernández C, Serna-Reyna L, Meraz-Rios M, Bandala C, Ortiz-Leon J, Salcedo M
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2014 Nov;35(11):11399-407

Vascular calcification is coupled with phenotypic conversion of vascular smooth muscle cells through Klf5-mediated transactivation of the Runx2 promoter.

Zhang J, Zheng B, Zhou PP, Zhang RN, He M, Yang Z, Wen JK
Bioscience reports 2014 Nov 4;34(6):e00148

Synthetic retinoid Am80 up-regulates apelin expression by promoting interaction of RARα with KLF5 and Sp1 in vascular smooth muscle cells.

Lv XR, Zheng B, Li SY, Han AL, Wang C, Shi JH, Zhang XH, Liu Y, Li YH, Wen JK
The Biochemical journal 2013 Nov 15;456(1):35-46

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Supportive validation

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Main image
Experimental details: Sample (30 ?g of whole cell lysate) A: H1299 10% SDS PAGE BTEB2 antibody GTX103289 diluted at 1:1000 The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Non-transfected (¡V) and transfected (+) 293T whole cell extracts (30 ?g) were separated by 10% SDS-PAGE, and the membrane was blotted with KLF5 antibody (GTX103289) diluted at 1:5000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Various whole cell extracts (30 ?g) were separated by 10% SDS-PAGE, and the membrane was blotted with KLF5 antibody (GTX103289) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Various whole cell extracts (30 ?g) were separated by 10% SDS-PAGE, and the membrane was blotted with KLF5 antibody (GTX103289) diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (GTX213110-01) was used to detect the primary antibody.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: Immunofluorescence analysis of paraformaldehyde-fixed mouse ESC D3, using KLF5(GTX103289) antibody at 1:200 dilution.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: KLF5 antibody detects KLF5 protein at nucleus by immunofluorescent analysis.Sample: HeLa cells were fixed in 4% paraformaldehyde at RT for 15 min.Green: KLF5 protein stained by KLF5 antibody (GTX103289) diluted at 1:500.Red: Phalloidin, a cytoskeleton marker, diluted at 1:100.Scale bar = 10 £gm.

Supportive validation

Submitted by: GeneTex (provider)
Main image
Experimental details: KLF5 antibody detects KLF5 protein at nucleus on HeLa xenograft by immunohistochemical analysis. Sample: Paraffin-embedded HeLa xenograft. KLF5 antibody (GTX103289) dilution: 1:500.