60355-1-Ig

antibody from Proteintech Group

Targeting: HAVCR2 CD366, FLJ14428, Tim-3, TIM3, TIMD3

Western blot (Data presented on provider website)

ELISA (Data presented on provider website)

Flow cytometry (Data presented on provider website)

Antibody Data

Product number

60355-1-Ig

Provider

Proteintech Group

Product name

TIM3 antibody

Antibody type

Monoclonal

Description

KD/KO validated TIM3 antibody (Cat. #60355-1-Ig) is a mouse monoclonal antibody that shows reactivity with human, pig, mouse, rat and has been validated for the following applications: FC, WB,ELISA.

Reactivity

Human, Mouse, Rat, Porcine

Host

Mouse

Conjugate

Unconjugated

Isotype

IgG

Antibody clone number

4C4G3

Vial size

20ul, 150ul

References

Submitted references

Aberrantly Expressed Galectin-9 Is Involved in the Immunopathogenesis of Anti-MDA5-Positive Dermatomyositis-Associated Interstitial Lung Disease.

Liang L, Zhang YM, Shen YW, Song AP, Li WL, Ye LF, Lu X, Wang GC, Peng QL
Frontiers in cell and developmental biology 2021;9:628128

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Up-Regulation of Immune Checkpoints in the Thymus of PRRSV-1-Infected Piglets in a Virulence-Dependent Fashion.

Ruedas-Torres I, Rodríguez-Gómez IM, Sánchez-Carvajal JM, Guil-Luna S, Larenas-Muñoz F, Pallarés FJ, Carrasco L, Gómez-Laguna J
Frontiers in immunology 2021;12:671743

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Molecular subtyping reveals immune alterations in IDH wild-type lower-grade diffuse glioma.

Wu F, Li GZ, Liu HJ, Zhao Z, Chai RC, Liu YQ, Jiang HY, Zhai Y, Feng YM, Li RP, Zhang W
The Journal of pathology 2020 Jul;251(3):272-283

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Tim‑3 regulates the ability of macrophages to counter lipopolysaccharide‑induced pulmonary epithelial barrier dysfunction via the PI3K/Akt pathway in epithelial cells.

Zhang Y, Zhang W
Molecular medicine reports 2020 Jul;22(1):534-542

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Cross-regulation by TLR4 and T cell Ig mucin-3 determines severity of liver injury in a CCl4-induced mouse model.

Zhao L, Liang J, Rao W, Cui M, Ren S, Zhang L, Xu D, Han Q, Zang YJ, Zhang B
Scandinavian journal of immunology 2020 Apr;91(4):e12851

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Role of Tim-3 in Decidual Macrophage Functional Polarization During Abnormal Pregnancy With Toxoplasma gondii Infection.

Zhang D, Ren L, Zhao M, Yang C, Liu X, Zhang H, Jiang Y, Sun X, Li T, Cui L, Hu X
Frontiers in immunology 2019;10:1550

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Tim-3 aggravates podocyte injury in diabetic nephropathy by promoting macrophage activation via the NF-κB/TNF-α pathway.

Yang H, Xie T, Li D, Du X, Wang T, Li C, Song X, Xu L, Yi F, Liang X, Gao L, Yang X, Ma C
Molecular metabolism 2019 May;23:24-36

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Tumor cell-intrinsic Tim-3 promotes liver cancer via NF-κB/IL-6/STAT3 axis.

Zhang H, Song Y, Yang H, Liu Z, Gao L, Liang X, Ma C
Oncogene 2018 May;37(18):2456-2468

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Low TIM3 expression indicates poor prognosis of metastatic prostate cancer and acts as an independent predictor of castration resistant status.

Wu J, Lin G, Zhu Y, Zhang H, Shi G, Shen Y, Zhu Y, Dai B, Ye D
Scientific reports 2017 Aug 21;7(1):8869