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Protein structure
PER1
Period circadian regulator 1PER, RIGUI
This gene is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers. Alternative splicing has been observed in this gene; however, these variants have not been fully described. [provided by RefSeq, Jan 2014]
Top validated antibodies |
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| Invitrogen Antibodies |  PA1-524 |
26 references | Polyclonal |
WB
ICC
IHC
OA
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| Proteintech Group | 13463-1-AP |
3 references | Polyclonal |
WB
EL
ICC
IHC
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| GeneTex | GTX128974 |
1 references | Polyclonal |
WB
ICC
IP
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| Wuhan Fine Biotech Co., Ltd. | FNab06311 |
Polyclonal |
WB
EL
ICC
IHC
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| Novus Biologicals | NBP2-24589 |
1 references | Polyclonal |
WB
IHC
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