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LearnNB100-2318
antibody from Novus Biologicals
Targeting: RCHY1
ARNIP, CHIMP, DKFZp586C1620, PIRH2, PRO1996, RNF199, ZCHY, ZNF363
Western blot
ImmunoprecipitationAntibody data
- Antibody Data
- Antigen structure
- References [9]
- Comments [0]
- Validations
- Western blot [1]
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- Product number
- NB100-2318 - Provider product page
- Provider
- Novus Biologicals
- Proper citation
- Novus Cat#NB100-2318, RRID:AB_10001841
- Product name
- Rabbit Polyclonal Pirh2 Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified.
- Reactivity
- Human
- Host
- Rabbit
- Isotype
- IgG
- Vial size
- 100 ul
- Concentration
- 1.0 mg/ml
- Storage
- Store at 4C. Do not freeze.
Submitted references p27kip1 Expression in non-small cell lung cancer is not an independent prognostic factor.
The Pirh2-keratin 8/18 interaction modulates the cellular distribution of mitochondria and UV-induced apoptosis.
Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains.
Molecular basis of Pirh2-mediated p53 ubiquitylation.
Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53.
Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells.
Activation of p53 in cervical cancer cells by human papillomavirus E6 RNA interference is transient, but can be sustained by inhibiting endogenous nuclear export-dependent p53 antagonists.
Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3.
Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer.
Sion-Vardy N, Freedman J, Lazarov I, Bolotin A, Ariad S
Anticancer research 2010 Sep;30(9):3699-704
Anticancer research 2010 Sep;30(9):3699-704
The Pirh2-keratin 8/18 interaction modulates the cellular distribution of mitochondria and UV-induced apoptosis.
Duan S, Yao Z, Zhu Y, Wang G, Hou D, Wen L, Wu M
Cell death and differentiation 2009 Jun;16(6):826-37
Cell death and differentiation 2009 Jun;16(6):826-37
Identification and characterization of two novel isoforms of Pirh2 ubiquitin ligase that negatively regulate p53 independent of RING finger domains.
Corcoran CA, Montalbano J, Sun H, He Q, Huang Y, Sheikh MS
The Journal of biological chemistry 2009 Aug 14;284(33):21955-70
The Journal of biological chemistry 2009 Aug 14;284(33):21955-70
Molecular basis of Pirh2-mediated p53 ubiquitylation.
Sheng Y, Laister RC, Lemak A, Wu B, Tai E, Duan S, Lukin J, Sunnerhagen M, Srisailam S, Karra M, Benchimol S, Arrowsmith CH
Nature structural & molecular biology 2008 Dec;15(12):1334-42
Nature structural & molecular biology 2008 Dec;15(12):1334-42
Phosphorylation of Pirh2 by calmodulin-dependent kinase II impairs its ability to ubiquitinate p53.
Duan S, Yao Z, Hou D, Wu Z, Zhu WG, Wu M
The EMBO journal 2007 Jul 11;26(13):3062-74
The EMBO journal 2007 Jul 11;26(13):3062-74
Differential response between the p53 ubiquitin-protein ligases Pirh2 and MdM2 following DNA damage in human cancer cells.
Duan W, Gao L, Wu X, Zhang Y, Otterson GA, Villalona-Calero MA
Experimental cell research 2006 Oct 15;312(17):3370-8
Experimental cell research 2006 Oct 15;312(17):3370-8
Activation of p53 in cervical cancer cells by human papillomavirus E6 RNA interference is transient, but can be sustained by inhibiting endogenous nuclear export-dependent p53 antagonists.
Koivusalo R, Mialon A, Pitkänen H, Westermarck J, Hietanen S
Cancer research 2006 Dec 15;66(24):11817-24
Cancer research 2006 Dec 15;66(24):11817-24
Myeloid leukemia factor 1 regulates p53 by suppressing COP1 via COP9 signalosome subunit 3.
Yoneda-Kato N, Tomoda K, Umehara M, Arata Y, Kato JY
The EMBO journal 2005 May 4;24(9):1739-49
The EMBO journal 2005 May 4;24(9):1739-49
Expression of Pirh2, a newly identified ubiquitin protein ligase, in lung cancer.
Duan W, Gao L, Druhan LJ, Zhu WG, Morrison C, Otterson GA, Villalona-Calero MA
Journal of the National Cancer Institute 2004 Nov 17;96(22):1718-21
Journal of the National Cancer Institute 2004 Nov 17;96(22):1718-21
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Supportive validation
- Submitted by
- Novus Biologicals (provider)
- Main image
- Experimental details
- Western Blot: Pirh2 Antibody [NB100-2318] - Detection of Human Pirh2 on HeLa whole cell lysate using NB100-2318.
