RPL26

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L24P family of ribosomal proteins. It is located in the cytoplasm. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. Mutations in this gene result in Diamond-Blackfan anemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2015]

Description

Ribosomal protein L26

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli, Endoplasmic reticulum, Cytosol

Predicted location

Intracellular

Protein family

Disease related genes
Human disease related genes
Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)
Ribosomal proteins

Chromosome

17 (8377516 - 8383213)

Ensembl ID

ENSG00000161970  (ver. 103.38)

Orthologs

Mouse Rpl26: ENSMUSG00000060938

UniProt

P61254

neXtProt

NX_P61254

Human splice variants
Mouse splice variants

Protein structure