APR03813G

antibody from Leading Biology

Targeting: PRCP HUMPCP, PCP

Western blot

Immunohistochemistry

Antibody data

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Validation data

Product number: APR03813G - Provider product page
Provider: Leading Biology
Product name: PRCP Antibody (N-term)
Antibody type: Polyclonal
Description: The protein encoded by this gene is a lysosomalprolylcarboxypeptidase, which cleaves C-terminal amino acids linkedto proline in peptides such as angiotension II, III anddes-Arg9-bradykinin. The cleavage occurs at acidic pH, but theenzyme activity is retained with some substrates at neutral pH.This enzyme has been shown to be an activator of the cellmatrix-associated prekallikrein. The importance of angiotension II,one of the substrates of this enzyme, in regulating blood pressureand electrolyte balance suggests that this gene may be related toessential hypertension. Alternatively spliced transcript variantsencoding distinct isoforms have been observed. [provided byRefSeq].
Reactivity: Human
Host: Rabbit
Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

PRCP protein structure - APR03813G shown in red.