APR03813G

PRCP antibody from Leading Biology
HUMPCP, PCP
Western blot
Recommended by provider
Immunohistochemistry
Recommended by provider

Antibody data

Product number
APR03813G
Provider
Leading Biology
Product name
PRCP Antibody (N-term)
Provider product page
Leading Biology - APR03813G
Antibody type
Polyclonal
Description
The protein encoded by this gene is a lysosomalprolylcarboxypeptidase, which cleaves C-terminal amino acids linkedto proline in peptides such as angiotension II, III anddes-Arg9-bradykinin. The cleavage occurs at acidic pH, but theenzyme activity is retained with some substrates at neutral pH.This enzyme has been shown to be an activator of the cellmatrix-associated prekallikrein. The importance of angiotension II,one of the substrates of this enzyme, in regulating blood pressureand electrolyte balance suggests that this gene may be related toessential hypertension. Alternatively spliced transcript variantsencoding distinct isoforms have been observed. [provided byRefSeq].
Reactivity
Human
Host
Rabbit
Storage
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
Provider Type Product Number
- No reagents -