WNT9A

The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It is expressed in gastric cancer cell lines. The protein encoded by this gene shows 75% amino acid identity to chicken Wnt14, which has been shown to play a central role in initiating synovial joint formation in the chick limb. This gene is clustered with another family member, WNT3A, in the chromosome 1q42 region. [provided by RefSeq, Jul 2008]

Description

Wnt family member 9A

Tissue specificity

Tissue enhanced (skeletal muscle)

Predicted location

Secreted to extracellular matrix

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Plasma proteins
Predicted secreted proteins

Chromosome

1 (227918656 - 227947932)

Ensembl ID

ENSG00000143816  (ver. 103.38)

Orthologs

Mouse Wnt9a: ENSMUSG00000000126

UniProt

O14904

neXtProt

NX_O14904

Human splice variants
Mouse splice variants

Protein structure