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- Antibody Data
- Antigen structure
- References [5]
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- Validations
- Flow cytometry [1]
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- Product number
- AF2940 - Provider product page
- Provider
- R&D Systems
- Product name
- Human CMG-2/ANTXR2 Antibody
- Antibody type
- Polyclonal
- Description
- Antigen Affinity-purified. Detects human CMG-2/ANTXR2 in direct ELISAs and Western blots. In direct ELISAs and Western blots, approximately 20% cross-reactivity with recombinant mouse CMG-2 is observed.
- Reactivity
- Human
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
P58335- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references Differential dependence on N-glycosylation of anthrax toxin receptors CMG2 and TEM8.
Therapeutic potential of capillary morphogenesis gene 2 extracellular vWA domain in tumour‑related angiogenesis.
Capillary morphogenesis gene 2 regulates adhesion and invasiveness of prostate cancer cells.
Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function.
Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin.
Friebe S, Deuquet J, van der Goot FG
PloS one 2015;10(3):e0119864
PloS one 2015;10(3):e0119864
Therapeutic potential of capillary morphogenesis gene 2 extracellular vWA domain in tumour‑related angiogenesis.
Ye L, Sun PH, Sanders AJ, Martin TA, Lane J, Mason MD, Jiang WG
International journal of oncology 2014 Oct;45(4):1565-73
International journal of oncology 2014 Oct;45(4):1565-73
Capillary morphogenesis gene 2 regulates adhesion and invasiveness of prostate cancer cells.
Ye L, Sanders AJ, Sun PH, Mason MD, Jiang WG
Oncology letters 2014 Jun;7(6):2149-2153
Oncology letters 2014 Jun;7(6):2149-2153
Bacillus anthracis lethal toxin reduces human alveolar epithelial barrier function.
Langer M, Duggan ES, Booth JL, Patel VI, Zander RA, Silasi-Mansat R, Ramani V, Veres TZ, Prenzler F, Sewald K, Williams DM, Coggeshall KM, Awasthi S, Lupu F, Burian D, Ballard JD, Braun A, Metcalf JP
Infection and immunity 2012 Dec;80(12):4374-87
Infection and immunity 2012 Dec;80(12):4374-87
Resistance of human alveolar macrophages to Bacillus anthracis lethal toxin.
Wu W, Mehta H, Chakrabarty K, Booth JL, Duggan ES, Patel KB, Ballard JD, Coggeshall KM, Metcalf JP
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 1;183(9):5799-806
Journal of immunology (Baltimore, Md. : 1950) 2009 Nov 1;183(9):5799-806
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of CMG-2/ANTXR2 in Human Monocytes by Flow Cytometry. Human whole blood monocytes were stained with Human CMG-2/ANTXR2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2940, filled histogram) or control antibody (Catalog # AB-108-C, open histogram), followed by Phycoerythrin-conjugated Anti-Goat IgG Secondary Antibody (Catalog # F0107).
