NOL7

The protein encoded by this gene localizes to the nucleolus, where it maintains nucleolar structure and cell growth rates. The encoded protein also functions as a tumor suppressor and regulator of angiogenesis. The RB tumor suppressor gene recruits transcription factors to this gene and positively regulates its expression. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]

Description

Nucleolar protein 7

Tissue specificity

Low tissue specificity

Subcell location

Nucleoli, Mitotic chromosome, Mitochondria

Predicted location

Intracellular

Protein family

Mapped to neXtProt
Mapped to UniProt SWISS-PROT
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Protein evidence (Kim et al 2014)

Chromosome

6 (13615335 - 13632739)

Ensembl ID

ENSG00000225921  (ver. 103.38)

Orthologs

Mouse Nol7: ENSMUSG00000063200

UniProt

Q9UMY1

neXtProt

NX_Q9UMY1

Human splice variants
Mouse splice variants

Protein structure