TYMP

This gene encodes an angiogenic factor which promotes angiogenesis in vivo and stimulates the in vitro growth of a variety of endothelial cells. It has a highly restricted target cell specificity acting only on endothelial cells. Mutations in this gene have been associated with mitochondrial neurogastrointestinal encephalomyopathy. Multiple alternatively spliced transcript variants have been identified. [provided by RefSeq, Apr 2012]

Description

thymidine phosphorylase

Protein family

Cancer-related genes, Disease related genes, Enzymes, FDA approved drug targets, Mapped to neXtProt, Mapped to UniProt SWISS-PROT, Plasma proteins, Predicted intracellular proteins, Protein evidence (Peptideatlas)

Chromosome

22:q13.33 (50525752 - 50530032)

Ensembl ID

ENSG00000025708  (ver. 99.38)

Orthologs

Mouse Tymp: ENSMUSG00000022615

UniProt

P19971

neXtProt

NX_P19971

Human splice variants
Mouse splice variants