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MFNG
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferaseThis gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the LFNG (GeneID: 3955) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene may control Notch signaling in claudin-low breast cancer. [provided by RefSeq, May 2018]
Top validated antibodies |
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| Everest Biotech |  EB11527 |
Polyclonal |
EL
ICC
IHC
FC
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| antibodies-online | ABIN2475483 |
1 references | Polyclonal |
EL
IHC
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| Affinity Biosciences | DF3837 |
Polyclonal |
WB
EL
ICC
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| Invitrogen Antibodies | PA5-101459 |
Polyclonal |
WB
ICC
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| R&D Systems | AF6355 |
Polyclonal |
WB
IP
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