Antibody data
- Antibody Data
- Antigen structure
- References [3]
- Comments [0]
- Validations
- Western blot [1]
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Validation data
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- Product number
- AF2387 - Provider product page
- Provider
- R&D Systems
- Product name
- Mouse BAMBI/NMA Antibody
- Antibody type
- Polyclonal
- Description
- Immunogen affinity purified. Detects mouse BAMBI/NMA in direct ELISAs and Western blots. In direct ELISAs, approximately 30% cross-reactivity with recombinant human BAMBI is observed.
- Reactivity
- Mouse
- Host
- Goat
- Conjugate
- Unconjugated
- Antigen sequence
Q9D0L6
- Isotype
- IgG
- Vial size
- 100 ug
- Concentration
- LYOPH
- Storage
- Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Submitted references BAMBI is expressed in endothelial cells and is regulated by lysosomal/autolysosomal degradation.
BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation.
TLR4 enhances TGF-beta signaling and hepatic fibrosis.
Xavier S, Gilbert V, Rastaldi MP, Krick S, Kollins D, Reddy A, Bottinger E, Cohen CD, Schlondorff D
PloS one 2010 Sep 24;5(9):e12995
PloS one 2010 Sep 24;5(9):e12995
BAMBI (bone morphogenetic protein and activin membrane-bound inhibitor) reveals the involvement of the transforming growth factor-beta family in pain modulation.
Tramullas M, Lantero A, Díaz A, Morchón N, Merino D, Villar A, Buscher D, Merino R, Hurlé JM, Izpisúa-Belmonte JC, Hurlé MA
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Jan 27;30(4):1502-11
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010 Jan 27;30(4):1502-11
TLR4 enhances TGF-beta signaling and hepatic fibrosis.
Seki E, De Minicis S, Osterreicher CH, Kluwe J, Osawa Y, Brenner DA, Schwabe RF
Nature medicine 2007 Nov;13(11):1324-32
Nature medicine 2007 Nov;13(11):1324-32
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Supportive validation
- Submitted by
- R&D Systems (provider)
- Main image
- Experimental details
- Detection of Mouse BAMBI/NMA by Western Blot. Western blot shows lysates of mouse liver tissue. PVDF Membrane was probed with 1 µg/mL of Goat Anti-Mouse BAMBI/NMA Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2387) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (Catalog # HAF019). A specific band was detected for BAMBI/NMA at approximately 32 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.